Background: The purpose of the present research was to analyse the impact of an educational message incorporating descriptive, explanatory, and directive information on the attitudes of young adults toward a peer with high-functioning autism (HFA). Method: Engineering students (N = 104) completed the Multidimensional Attitudes Scale at 3 time points--before the educational message, afterward, then 1 month later. The message was delivered through a video with a voice-over or live by an actor playing the role of an adult with HFA in a situation of personalised interaction. Results: Participants in the personalised interaction condition displayed significantly more positive attitudes than participants in control group and voice-over conditions. Conclusions: Even a brief educational message, combined with a situation of personalised interaction, can influence adults' attitudes. Generalisation of such an improvement to the outgroup (i.e., people on the spectrum) shall be discussed.