Empirical studies of creativity emphasize the importance of ambiguity advantage in idea generation and creative problem-solving. This study examined whether ambiguous figures could directly induce a mind-set that would transfer to the creative problem-solving. In Experiment 1, we examined whether presentation of ambiguous figures would influence participants' performance in alternative uses tasks, and the results showed that prior exposure to ambiguous figures significantly enhanced participants' performance in the dimension of fluency, flexibility, and originality than those exposed to non-ambiguous figures; in general uses tasks, there were no significant difference in the reaction time and originality between the ambiguous figure condition and non-ambiguous figure condition. In Experiment 2, the facilitative effect of ambiguous figures on creative thinking was further examined with creative story generation tasks that demand more mental effort and increased cognitive load. Results showed that creativity of stories generated in ambiguous figure condition was scored significantly higher than those in non-ambiguous figure condition. The current research extends our understanding of the facilitative effect of ambiguous figures on creative problem-solving.