The association of autism spectrum disorder (ASD) with self-reported maternal cannabis use from 3 months pre-conception to delivery ("peri-pregnancy") was assessed in children aged 30-68 months, born 2003 to 2011. Children with ASD (N = 1428) were compared to children with other developmental delays/disorders (DD, N = 1198) and…

We estimated risk factors associated with suspected neuropsychomotor developmental delay at age 2 years, in a birth cohort in the Brazilian Amazon. The Maternal and Child Health and Nutrition in Acre (MINA-Brasil) study is a population-based birth cohort involving children born between July 2015 and June 2016 in the municipality of Cruzeiro do…

Genetics, environment, and their interactions impact autism spectrum disorder etiology. Smoking is a suspected autism spectrum disorder risk factor due to biological plausibility and high prevalence. Using two large epidemiological samples, we examined whether autism spectrum disorder was associated with prenatal paternal smoking in a Discovery…

The objective of this retrospective analysis of the longitudinal Millennium Cohort Study was to examine whether maternal alcohol consumption in pregnancy (MACP) is associated with the development of childhood autism spectrum disorders (ASD). Data on MACP and ASD were obtained from parental questionnaires. There were 18,168 singleton mother-child…

Identification of language disorders in children younger than 3 years remains challenging despite agreement that early intervention improves outcomes. This study of twin language and gesture development substantiated the twinning effect, an unexplained lag in expressive and receptive language seen in twins, for a group of 88, 16- to 18-month-old…

The evidence for negative influences of maternal stress during pregnancy on child cognition remains inconclusive. This study tested the association between maternal prenatal stress and child intelligence in 4,251 mother-child dyads from a multiethnic population-based cohort in the Netherlands. A latent factor of prenatal stress was constructed,…

Infantile spasms (IS) is a rare epileptic disorder occurring in children under the age of one that can often lead to severe developmental delays throughout life. Though over 200 etiologies have been associated with this disorder, many cases remain unexplained. Research into the etiology of IS has implicated causes such as exposure to prenatal…

Identifying children at the risk of developmental delay can improve their long-term prognosis. In this case--control study, mothers and infants aged 6--18 months referred to healthcare centres affiliated with Qazvin University of Medical Sciences were recruited from August to December 2017. The sample size consisted of 197 individuals in…

Iron consumption among mothers has recently been found to decrease the risk of autism in offspring. However, epidemiological evidence of an increasing iron deficiency among mothers or infants is lacking, and evidence within an individual-level framework of iron deficiency confers doubt upon iron's role as a direct cause of autism. We attempt to…

Opioid use during pregnancy is associated with suboptimal pregnancy outcomes. Little is known about child neurodevelopmental outcomes. We examined associations between maternal opioid prescriptions preconception to delivery (peri-pregnancy) and child's risk of ASD, developmental delay/disorder (DD) with no ASD features, or ASD/DD with autism…

Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder that brings heavy burdens to families and the society. This case-control study explored risk factors for ASD based on 74,252 children aged 3-12 years who were recruited from general education kindergartens, primary schools, and special education schools in Shanghai, China.…

The article addresses clinical, neurodevelopmental, and psychological experiences of pregnant parents to build the case for shifting therapeutic approaches to promote the earliest possible connections between parents and their infant. The article emphasizes the rationale for therapeutic interface with families in pregnancy as it relates to stress…

This paper is an attempt to highlight the ways through which expected parents can support their children for their development from the time of conception till birth. This paper shares ideas to the parents about stimulation, which children are required for their development. This paper is divided into three categories: First trimester, second…

Emerging evidence suggests that prenatal stress does not solely undermine child functioning but increases developmental plasticity to both negative and positive postnatal experiences. Here we test this proposition using the Norwegian Mother and Child Cohort study while implementing an extreme-group (i.e., high vs. low prenatal stress) design (n =…

Prenatal maternal depression affects both mother and fetus with long-term implications for offspring vulnerability to psychopathology through alterations to brain development, stress physiology, negative emotionality, and cognitive control. This article reviews evidence for the negative impact of prenatal maternal depression on offspring…