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Direct linkPodlesnik, Christopher A.; Jimenez-Gomez, Corina; Woods, James H. – Journal of the Experimental Analysis of Behavior, 2010
The goal of this series of experiments was to develop an operant choice procedure to examine rapidly the punishing effects of intravenous drugs in rats. First, the cardiovascular effects of experimenter-administered intravenous histamine, a known aversive drug, were assessed to determine a biologically active dose range. Next, rats responded on…
Descriptors: Positive Reinforcement, Drug Use, Animals, Punishment
