Purpose: The ultimate goal of aphasia therapy should be to achieve gains in function that generalize to untrained exemplars and daily conversation. Anomia is one of the most disabling features of aphasia. The predominantly lexical/semantic approaches used to treat anomia have low potential for generalization due to the orthogonality of semantic…

We report the case of an English-speaking aphasic patient (JP) with left posterior-frontal damage affecting the inferior frontal and precentral gyri. In speaking, JP was impaired with the regular inflections of nouns and pseudonouns, making errors like "pears" instead of "pear" or "door" for "doors", while the spoken production of noun stems and…

The neuropsychological features of the primary progressive aphasia (PPA) syndromes continue to be defined. Here we describe a detailed neuropsychological case study of a patient with a mutation in the progranulin ("GRN") gene who presented with progressive word-finding difficulty. Key neuropsychological features in this case included gravely…

Two experiments investigated phonological, derivational-morphological and semantic aspects of grammatical gender assignment in a perception and a production task in German aphasic patients and age-matched controls. The agreement of a gender indicating adjective (feminine, masculine or neuter) and a noun was evaluated during perception in…

A semantic-based treatment was used initially to train naming of nouns in four adults with aphasia. Treatment responses and error patterns indicated treatment resulted in improved naming of both trained and untrained items for two participants. Two other participants showed improved naming only after phonological information was added. Results…