Background: While pragmatic deficits are well documented in patients with schizophrenia (SCZ) and right hemisphere damage (RHD), there is a paucity of research comparing the pragmatic deficits of these two groups. Do they experience similar cognitive dysfunction or is there a dissociation between the two patient groups? Aims: To investigate the…

Autism spectrum disorders (ASD) and schizophrenia represent different mental disorders, but intriguing similarities seem to appear.In the present meta-analysis, we examined theory of mind (ToM) impairments in adults with ASD or schizophrenia based on studies that have compared the two patient groups directly by using the same test-battery at the…

This study examined hospitalizations in a large, all-payer, nationally representative sample of inpatient hospitalizations in the US and identified differences in rates of hospitalization for conditions by race and ethnicity in autistic adults. Conditions examined included mood disorders, epilepsy, schizophrenia, and ambulatory care sensitive…

The clinical similarity among different neuropsychiatric disorders (NPDs) suggested a shared genetic basis. We catalogued 23,109 coding de novo mutations (DNMs) from 6511 patients with autism spectrum disorder (ASD), 4,293 undiagnosed developmental disorder (UDD), 933 epileptic encephalopathy (EE), 1022 intellectual disability (ID), 1094…

Background: Patients with schizophrenia present with both cognitive impairment as well as language difficulties. There are similarities in the language output of patients with schizophrenia and patients with aphasia, thus a differential diagnosis of patients who present with a question of dual diagnoses can be a clinical challenge. This case…

Medication noncompliance is a significant challenge in managing schizophrenia, a chronic and severe mental health disorder characterized by symptoms such as delusions, hallucinations, disorganized thinking, and impaired functioning. Schizophrenia presents both positive symptoms, which involve exaggerated thoughts or behaviors, and negative…

Background: Positive symptoms of schizophrenia are associated with significant difficulties in daily functioning, and these difficulties have been associated with impaired executive functions (EEFF). However, specific cognitive and socio-emotional executive deficits have not been fully established. Objective: The present study has several…

We examined the basis of feeling-of-knowing judgments (FOK) in patients with schizophrenia. Such patients typically have impaired memory and awareness, but not metamemory-accuracy deficits. The magnitude of FOKs are lower for patients with schizophrenia than for healthy participants, but judgments equally predict memory performance. In healthy…

Background: Addressing goals of care involves an added layer of complexity in never-competent patients. The concept of best interests is used to guide decision-making for these patients; however, this can be difficult for many reasons. To help providers recognise and minimise these challenges, we recommend steps that can be taken to support…

Mitochondrial dysfunction has been linked to many psychiatric disorders. Ketogenic diets have been shown to reduce mitochondrial dysfunction and thus may be helpful to patients who suffer from these disorders. In this article, we review the effects of a ketogenic diet in patients with psychiatric disorders such as autism, depression, anxiety, and…

Social cognition impairment is a core shared phenotype in both schizophrenia spectrum disorders (SSD) and autism spectrum disorders (ASD). This study compares social cognition performance through four different instruments in a sample of 147 individuals with ASD or SSD and in healthy controls. We found that both clinical groups perform similarly…

Impaired insight is common in schizophrenia. Etiological models focusing on single determinants have not succeeded in explaining insight deficits. More complex models seem promising. This study tests Startup's (1996) model of insight and cognition, predicting a curvilinear relationship and specific insight-cognition configurations. Patients with…

Education during recovery could impact a forensic psychiatric patient's community reintegration; however, individual education goals for patients can be difficult due to the lack of available parameters. The purpose of this study was to test whether age at first hospitalization is predictive of educational attainment among forensic psychiatric…

The similarities between high functioning autism (HFA) and schizotypal-schizoid personality disorder (SSPD) in terms of social cognition and interpersonal deficits may lead to confusion in symptom interpretation, and consequently result in misdiagnosis. Thus, this study aims to investigate differences in mentalizing with particular interest on the…

The present study examined 12 abnormal psychology textbooks to determine whether Rosenhan's classic study, "Being sane in insane places," was covered, and if so, the nature of that coverage. Only 50% covered the study, with all describing the study as demonstrating the biasing power of psychiatric labels. Two key aspects of the study…