"Diagnose" is a computer-assisted instruction lesson designed to give medical students experience in using deductive reasoning in diagnosis. The computer selects a mystery disease from a stored list, along with 12 randomly-selected clues--three indicators of presenting complaints, history, physical findings, and laboratory tests. (LBH)

Compared the effects of fixed-interval and on-demand administration of analgesic medications in chronic pain patients. A fixed-interval analgesic schedule was found more effective than an on-demand schedule in reducing subjective pain and elevating mood. No differences were found between the two conditions on measures of physical activity.…

In a survey of pre-clinical students' views on being told their diagnosis and prognosis in the hypothetical case of cancer, high agreement in the proportion wanting to be or not to be told was found between the responses of students and a sample of cancer patients reported by Kelly and Friesen. (Author/LBH)

Showed that Minnesota Multiphasic Personality Inventory (MMPI) scores for adolescent and adult victims of rheumatic fever (N=162) were generally lower than Mayo Clinic norms. Significant age effects confirm findings that adolescents score higher on the MMPI. Found patients without carditis scored higher than carditis patients, contrary to…

The health locus of control scale was used to compare mastectomy patients who received counseling to patients not receiving counseling. Posttreatment group means in the locus of control were accounted for by changes on the fate subscale. Validity of this scale for populations characterized by different health problems is discussed. (Author)

The author proposes the training of physicians in the use of a protocol to help a patient draw up a Living Will. The successful use of such a training protocol could begin to meet the existing need for a more structured education in the care of the terminally ill and to minimize uncertainty by achieving standards of uniformity in this aspect of…

Nearly two centuries ago, Parkinson (1817) first observed that a particular pattern of speech changes occur in patients with idiopathic Parkinson's disease (PD). Numerous studies have documented these changes using a wide variety of acoustic measures, and yet few studies have attempted to quantify any such changes longitudinally, through the early…

Neutralizing antibodies (NAb) against interferon-[Beta] (IFN-Beta) develop in about a third of treated multiple sclerosis patients and are believed to reduce therapeutic efficacy of IFN-[Beta] on clinical and MRI measures. The expression of the interferon acute-response protein, myxovirus resistance protein A (MxA) is a sensitive measure of the…

The purpose of this study was to investigate the issue of age-limited learning effects on visual lexical decision in normal and pathological aging, by using words with different frequency trajectories and cumulative frequencies. We selected words that objectively changed in frequency trajectory from an early word count (Thorndike, 1921, 1932;…

Genital human papillomavirus (HPV) is the most prevalent and widespread sexually transmitted disease and is responsible for almost all cases of cervical cancer worldwide. However, HPV has received little public health attention, is not a reportable STD, and often is absent from the repertoire of STDs. In addition, there is pervasive misinformation…

This study examined how Parkinson's disease patients cope with disease-related stressors over time. Of interest was whether patterns of coping would support a dispositional model of coping (i.e., stability) or a contextual model of coping (i.e., change). The influence of stability and change in coping on mental and physical health outcomes was…

Introduction: Much of the international community has an increased awareness of potential biologic, chemical, and nuclear threats and the need for physicians to rapidly acquire new knowledge and skills in order to protect the public's health. The present study evaluated the educational effectiveness of an online bioterrorism continuing medical…

Background: Apraxia is neurologically induced deficit in the ability perform purposeful skilled movements. One of the most common forms is ideomotor apraxia (IMA) where spatial and temporal production errors are most prevalent. IMA can be associated Alzheimer's disease (AD), even early in its course, but is often not identified possibly because…

The study investigated the general population's perceived infectivity of asymptomatic and recovered severe acute respiratory syndrome (SARS) patients and factors associated with avoidance and discriminatory attitudes, including demographic background, SARS-related perceptions and emotional response to the SARS epidemic. A population-based survey…