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Dubois, A.; Boudjarane, M.; Le Fur-Bonnabesse, A.; Dion, A.; L'heveder, G.; Quinio, B.; Walter, M.; Marchand, S.; Bodéré, C. – Journal of Autism and Developmental Disorders, 2020
We tested endogenous pain modulation mechanisms in adults with autism spectrum disorders (ASD). Nineteen ASD adults without intellectual disabilities were included, matched with 19 healthy volunteers on the basis of sex and chronological age. An experimental pain model was used to measure excitatory and inhibitory pain mechanisms in a single…
Descriptors: Pain, Adults, Autism, Pervasive Developmental Disorders
Vaughan, Sarah; McGlone, Francis; Poole, Helen; Moore, David J. – Journal of Autism and Developmental Disorders, 2020
Sensory abnormalities in autism has been noted clinically, with pain insensitivity as a specified diagnostic criterion. However, there is limited research using psychophysically robust techniques. Thirteen adults with ASD and 13 matched controls completed an established quantitative sensory testing (QST) battery, supplemented with measures of pain…
Descriptors: Autism, Pervasive Developmental Disorders, Adults, Sensory Experience
Kurtz-Nelson, Evangeline C.; Tham, See Wan; Ahlers, Kaitlyn; Cho, Daniel; Wallace, Arianne S.; Eichler, Evan E.; Bernier, Raphael A.; Earl, Rachel K. – Journal of Autism and Developmental Disorders, 2021
Self-injurious behaviors (SIB) are elevated in autism spectrum disorder (ASD) and related genetic disorders, but the genetic and biological mechanisms that contribute to SIB in ASD are poorly understood. This study examined rates and predictors of SIB in 112 individuals with disruptive mutations to ASD-risk genes. Current SIB were reported in 30%…
Descriptors: Self Destructive Behavior, Injuries, Autism, Pervasive Developmental Disorders
Fründt, Odette; Grashorn, Wiebke; Schöttle, Daniel; Peiker, Ina; David, Nicole; Engel, Andreas K.; Forkmann, Katarina; Wrobel, Nathalie; Münchau, Alexander; Bingel, Ulrike – Journal of Autism and Developmental Disorders, 2017
Altered sensory perception has been found in patients with autism spectrum disorders (ASD) and might be related to aberrant sensory perception thresholds. We used the well-established, standardized Quantitative sensory testing (QST) protocol of the German Research Network on Neuropathic Pain to investigate 13 somatosensory parameters including…
Descriptors: Pervasive Developmental Disorders, Autism, Sensory Experience, Adults
ten Hoopen, Leontine W.; de Nijs, Pieter F. A.; Duvekot, Jorieke; Greaves-Lord, Kirstin; Hillegers, Manon H. J.; Brouwer, Werner B. F.; Hakkaart-van Roijen, Leona – Journal of Autism and Developmental Disorders, 2020
This study investigated health-related QoL (HRQoL) and care-related quality of life (CarerQol) in clinically referred children with an autism spectrum disorder (ASD), and their primary and secondary caregivers. The EuroQol five-dimensional (EQ-5D) and the CarerQol questionnaires were used to respectively measure health-related QoL and care-related…
Descriptors: Quality of Life, Autism, Pervasive Developmental Disorders, Caregivers
Chakraborty, Payal; Carpenter, Kimberly L. H.; Major, Samantha; Deaver, Megan; Vermeer, Saritha; Herold, Brianna; Franz, Lauren; Howard, Jill; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2021
Individuals with autism spectrum disorder are more likely than typically developing individuals to experience a range of gastrointestinal abnormalities, including chronic diarrhea, constipation, food sensitivities, and abdominal pain. These gastrointestinal symptoms have been associated with higher levels of irritability and aggressive behavior,…
Descriptors: Autism, Pervasive Developmental Disorders, Human Body, At Risk Persons
Wark, Stuart; Kingstone, Martin – Journal of Intellectual & Developmental Disability, 2019
Background: This descriptive single-case study reports upon a four-decade history of health care and support provided to one male with life-long intellectual disability and significant comorbidities. Methods: All available paper and electronic documentation from the past 40 years was reviewed, with relevant health and medication information…
Descriptors: Comorbidity, Health Services, Intellectual Disability, Documentation
Richards, Caroline; Davies, Louise; Oliver, Chris – Journal of Autism and Developmental Disorders, 2017
Self-injury is common in autism spectrum disorder (ASD); however few studies have investigated correlates of self-injury or the putative associations with self-restraint. Questionnaire data on self-injury, self-restraint, health conditions, overactivity/impulsivity and repetitive/restricted behavior were collected on 208 children and 216 adults…
Descriptors: Autism, Pervasive Developmental Disorders, Injuries, Self Destructive Behavior
Failla, Michelle D.; Moana-Filho, Estephan J.; Essick, Greg K.; Baranek, Grace T.; Rogers, Baxter P.; Cascio, Carissa J. – Autism: The International Journal of Research and Practice, 2018
Pain assessments typically depend on self-report of the pain experience. Yet, in individuals with autism spectrum disorders, this can be an unreliable due to communication difficulties. Importantly, observations of behavioral hypo- and hyperresponsivity to pain suggest altered pain sensitivity in autism spectrum disorder. Neuroimaging may provide…
Descriptors: Autism, Pervasive Developmental Disorders, Brain Hemisphere Functions, Responses
Garcia-Villamisar, D.; Moore, D.; Garcia-Martínez, M. – Journal of Autism and Developmental Disorders, 2019
Research on pain in autism spectrum disorder (ASD) is in its infancy, with almost nothing known about how individual differences may predicting pain response in ASD. In the present study, 45 adults (28 male, age 22-48 years) with diagnoses of autism and intellectual delay were observed during vaccination or dental cleaning and their pain…
Descriptors: Autism, Pervasive Developmental Disorders, Pain, Clinical Diagnosis
De Coster, Lize; Wiersema, Jan R.; Deschrijver, Eliane; Brass, Marcel – Autism: The International Journal of Research and Practice, 2018
Autism spectrum disorder is a neurodevelopmental disorder that is associated with problems in empathy. Recent research suggests that impaired control over self-other overlap based on motor representations in individuals with autism spectrum disorder might underlie these difficulties. In order to investigate the relationship of self-other…
Descriptors: Pain, Empathy, Autism, Imitation
Beetz, Andrea M. – Applied Developmental Science, 2017
Different positive effects of interactions with animals, such as reduction of stress reactions, depressive mood, anxiety, aggression, and pain, and promotion of trust, calmness, motivation, and concentration have been documented by research on human-animal interaction (HAI), including animal assisted interventions (AAIs). Potential biological,…
Descriptors: Animals, Depression (Psychology), Anxiety, Caregivers
Thaler, Hanna; Skewes, Joshua C.; Gebauer, Line; Christensen, Peer; Prkachin, Kenneth M.; Jegindø Elmholdt, Else-Marie – Autism: The International Journal of Research and Practice, 2018
Difficulties in emotion perception are commonly observed in autism spectrum disorder. However, it is unclear whether these difficulties can be attributed to a general problem of relating to emotional states, or whether they specifically concern the perception of others' expressions. This study addressed this question in the context of pain, a…
Descriptors: Pain, Autism, Pervasive Developmental Disorders, Emotional Response
Moore, David J. – Autism: The International Journal of Research and Practice, 2015
In addition to the diagnostic criteria for autism spectrum disorder, a number of clinically important comorbid complaints, including sensory abnormalities, are also discussed. One difference often noted in these accounts is hyposensitivity to pain; however, evidence for this is limited. The purpose of the current review therefore was to examine…
Descriptors: Autism, Pervasive Developmental Disorders, Pain, Comorbidity
Courtemanche, Andrea B.; Black, William R.; Reese, R. Matthew – American Journal on Intellectual and Developmental Disabilities, 2016
Research has suggested that individuals who engage in self-injurious behavior may have enhanced expressions of pain, which contradicts previous assertions of blunted pain sensitivity in this population. The purpose of this study was to measure expressions of pain among young children being evaluated for autism and other neurodevelopmental…
Descriptors: Injuries, Self Destructive Behavior, Behavior Problems, Young Children