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Kutcher, Stan; Murphy, Andrea; Gardner, David – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
The article examines the World Health Organization's Model List of Essential Medicines (EML) and suggests modification for appropriate psychopharmacological treatment of child- and adolescent-onset mental disorders. The EML enlists few of the psychotropic medicines that are useful for the treatment of young people thereby limiting the…
Descriptors: Mental Disorders, Pharmacology, Drug Therapy, Mental Health
de Boissezon, Xavier; Peran, Patrice; de Boysson, Chloe; Demonet, Jean-Francois – Brain and Language, 2007
Pharmacotherapy of aphasia had been discussed for the last twenty years with first bromocriptine and amphetamine and then serotoninergic, GABAergic and cholinergic agents. Here, we reviewed the MEDLINE available reports of drug therapy for aphasia. So far, proofs of efficiency were found indubitable for none of the studied molecules. However, some…
Descriptors: Aphasia, Drug Therapy, Speech Therapy, Outcomes of Treatment
Bleiweiss, Jamie – ProQuest LLC, 2009
Problem behavior significantly impedes multiple aspects of quality of life for individuals with developmental disabilities, and thus represents a major priority for intervention. Psychotropic medications are commonly administered to treat such behavior; however, these agents are often associated with adverse side effects that may have a negative…
Descriptors: Intervention, Quality of Life, Developmental Disabilities, Drug Therapy
Roberts, Holly J.; Floress, Margaret T.; Ellis, Cynthia R. – Psychology in the Schools, 2009
The number of children taking psychotropic medications has dramatically increased in recent years. These children typically take medication during school hours, thereby making the school setting an optimal venue in which evaluate the effectiveness of medications. Given their training in data-based decision making, intervention, and assessment,…
Descriptors: School Psychologists, Pharmacology, School Psychology, Ethics
Broadstock, Marita; Doughty, Carolyn; Eggleston, Matt – Autism: The International Journal of Research and Practice, 2007
The variable expression of autism over the lifespan is likely to lead to different symptoms and support requirements, and to distinct responses to pharmacotherapy treatment, in older patients compared to children. This systematic review considers the effectiveness of pharmacological treatment in managing autism spectrum disorder in adolescents and…
Descriptors: Patients, Age Differences, Literature Reviews, Adolescents
Emslie, Graham J.; Waslick, Bruce; Weller, Elizabeth B.; Kloos, Angelica; Weller, Ronald A.; Kratochvil, Christopher J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
A 15-year-old male presents with moderately severe depression, and fluoxetine 20 mg is initiated. When he returns 14 days later, he describes suicidal ideations for the first time. He has recurrent thoughts of wishing he were dead, a plan, but no intent to act. How would this affect medication management? This article presents the opinions of five…
Descriptors: Suicide, Depression (Psychology), Males, Adolescents
Deb, S.; Sohanpal, S. K.; Soni, R.; Lenotre, L.; Unwin, G. – Journal of Intellectual Disability Research, 2007
Background: Psychopharmacological intervention in the management of behaviour problems in adults with intellectual disabilities (ID) has become a common treatment strategy. This has become a cause for concern, given that the evidence for its effectiveness is uncertain and most drugs are not licensed for this use. Methods: A comprehensive…
Descriptors: Intervention, Scientific Methodology, Mental Retardation, Pharmacology
Khanzode, Leena A.; Saxena, Kirti; Kraemer, Helena; Chang, Kiki; Steiner, Hans – Child Psychiatry and Human Development, 2006
Little is known about how deeply medication treatment penetrates different levels of the mind/brain system. Psychopathology consists of relatively simple constructs (e.g., anger, irritability), or complex ones (e.g., responsibility). This study examines the efficacy of a specific compound, divalproex sodium (DVPX), on the various levels of…
Descriptors: Profiles, Pharmacology, Psychopathology, Drug Therapy
Findling, Robert L.; McNamara, Nora K.; Stansbrey, Robert; Gracious, Barbara L.; Whipkey, Resaca E.; Demeter, Christine A.; Reed, Michael D.; Youngstrom, Eric A.; Calabrese, Joseph R. – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: It has been reported that bipolar disorder may become less responsive to previously effective treatment with each symptomatic relapse. The primary goal of this study was to assess the rate of restabilization after the resumption of lithium ([Li[superscript +]) plus divalproex (DVPX) following relapse on either agent as monotherapy.…
Descriptors: Drug Therapy, Patients, Mental Disorders, Depression (Psychology)
Donnelly, Craig L.; Wagner, Karen Dineen; Rynn, Moira; Ambrosini, Paul; Landau, Phyllis; Yang, Ruoyong; Wohlberg, Christopher J. – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To explore time to first response and time to first persistent response of sertraline versus placebo and compare these parameters between children (6-11 years old, n = 177) and adolescents (12-17 years old, n = 199) with major depressive disorder. Method: A 10-week placebo-controlled treatment was followed by a 24-week open-label…
Descriptors: Adolescents, Depression (Psychology), Drug Therapy, Comparative Analysis
Matson, Johnny L.; Gonzalez, Melissa L.; Smith, Kimberly R.; Terlonge, Cindy; Thorson, Ryan T.; Dixon, Dennis R. – Research in Developmental Disabilities: A Multidisciplinary Journal, 2006
A substantial literature on the effective treatment of bipolar disorder has begun to appear, particularly in the last 20 years.The majority of treatments studied have employed medications, particularly mood stabilizers, a typical antipsychotics and antidepressants. Most treatments produce side effects and medications are no exception. A review of…
Descriptors: Cost Effectiveness, Pharmacology, Mental Retardation, Drug Therapy

Lewis, Mark H. – Journal of Autism and Developmental Disorders, 1996
This paper reviews recent findings on the efficacy of psychopharmacological interventions in autism, points out gaps in knowledge of the effects of specific drug classes, and suggests research directions for the future. (Author/DB)
Descriptors: Autism, Drug Therapy, Intervention, Outcomes of Treatment
Spencer, Thomas J.; Faraone, Stephen V.; Biederman, Joseph; Lerner, Marc; Cooper, Kimberly M.; Zimmerman, Brenda – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To investigate whether prolonged therapy with a long-acting stimulant affects growth in children with attention-deficit/hyperactivity disorder (ADHD). Method: One hundred seventy-eight children ages 6 to 13 years received OROS methylphenidate (OROS MPH, CONCERTA) for at least 21 months. Height and weight were measured monthly during the…
Descriptors: Body Height, Body Weight, Drug Therapy, Stimulants
McGough, James; McCracken, James; Swanson, James; Riddle, Mark; Kollins, Scott; Greenhill, Laurence; Abikoff, Howard; Davies, Mark; Chuang, Shirley; Wigal, Tim; Wigal, Sharon; Posner, Kelly; Skrobala, Anne; Kastelic, Elizabeth; Ghuman, Jaswinder; Cunningham, Charles; Shigawa, Sharon; Moyzis, Robert; Vitiello, Benedetto – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: The authors explored genetic moderators of symptom reduction and side effects in methylphenidate-treated preschool-age children diagnosed with attention-deficit/hyperactivity disorder (ADHD). Method: DNA was isolated from 81 subjects in a double-blind, placebo-controlled, crossover methylphenidate titration. Parents and teachers…
Descriptors: Hyperactivity, Genetics, Attention Deficit Disorders, Drug Therapy

Hollon, Steven D.; And Others – Journal of Consulting and Clinical Psychology, 1991
Reviews use of cognitive therapy (CT) for depression compared to use of tricyclic pharmacotherapy in nonbipolar outpatients. Suggests that CT may be roughly comparable in treatment of the acute episode, combined CT-pharmacotherapy does not appear to be clearly superior to either modality, and CT treatment during the acute episode may reduce the…
Descriptors: Cognitive Restructuring, Depression (Psychology), Drug Therapy, Outcomes of Treatment