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Ball, S. L.; Holland, A. J.; Watson, P. C.; Huppert, F. A. – Journal of Intellectual Disability Research, 2010
Background: Recent research has suggested a specific impairment in frontal-lobe functioning in the preclinical stages of Alzheimer's disease (AD) in people with Down's syndrome (DS), characterised by prominent changes in personality or behaviour. The aim of the current paper is to explore whether particular kinds of change (namely executive…
Descriptors: Mental Retardation, Alzheimers Disease, Diseases, Personality