Identification of cardiometabolic risk (CMR) in U.S. younger population by assessing muscular strength via handgrip (HG) dynamometry may aid in prevention efforts. Currently, no nationally representative HG cut-points are available for identifying increased CMR in U.S. adolescents or young adults. In this study, we propose normalized grip strength (NGS) cut-points for U.S. younger population CMR identification. National Health and Nutrition Examination Survey 2011-2012 and 2013-2014 data sets were used for analysis. A total of 1,033 participants (female [F], n = 498; male [M], n = 535) aged 12-24 years without current infection were included in analyses. The identified age- and sex-specific NGS cut-points are: M = 0.39 and F = 0.34 (age = 12-17 years), M = 0.45 and F = 0.34 (age = 18-24 years). These cut-points may be used in U.S. public health screening routines such as school- or community-based health-related fitness surveillance programs. Future work should use these cut-points in various samples to test their predictive utility for increased CMR.