Community health workers have been shown to be an effective way to improve health outcomes in under-resourced contexts like South Africa. Community health workers can support health and well-being through supporting mother-infant bonding, which is associated with a wide range of benefits. The bond between mother and infant is critical for infants' health, nutrition, care, and future development. However, mother-infant bonding faces many challenges in South Africa, including poverty, poor health care, lack of education, maternal depression, substance abuse, and high rates of crime and violence. Thus, the aim of this study was to explore how community health workers might enhance mother-infant bonding. Semistructured interviews were conducted with 15 community health workers. A thematic analysis suggests that that there are many contextual inhibitors of mother-infant bonding, that support is vital for mother-infant bonding, and that community health workers provide comprehensive, holistic support.