Discusses computational studies of learning in artificial neural networks and findings that may provide insights into the learning abilities of the human brain. Describes efforts to test theories about brain information processing, using artificial neural networks. Vignettes include information concerning how a neural network represents…

A theory of normal and delayed development of language is presented, arguing that linguistic capacity develops in gradual, sequential, critically timed phases; children with slowly developing brains have delays in storing utterances; a critical period for activation of experience-dependent grammatical mechanisms declines without optimal result;…

This article summarizes work in progress at the Bowman Gray School of Medicine (North Carolina) on the structure and physiological profiles of reading disability and relates the findings to core left-hemisphere language functions. Data add evidence of the structural anomalies associated with dyslexia and evidence of its heritability, especially of…

Acetylcholine release in sensory neocortex contributes to higher-order sensory function, in part by activating nicotinic acetylcholine receptors (nAChRs). Molecular studies have revealed a bewildering array of nAChR subtypes and cellular actions; however, there is some consensus emerging about the major nAChR subtypes and their functions in…

Background: Childhood onset schizophrenia (COS) is a rare but severe form of the adult onset disorder. While structural brain imaging studies show robust, widespread, and progressive gray matter loss in COS during adolescence, there have been no longitudinal studies of sufficient duration to examine comparability with the more common adult onset…

Recently, knowledge of the mechanisms of visual-spatial attention has improved due to studies employing single cell recording with alert monkeys and studies using performance analysis of neurological patients. These studies suggest that a complex neural network including parts of the posterior parietal lobe and midbrain are involved in covert…

Describes some of the common principles underlying the operation of the cortex in an effort to understand the human brain. Discusses the structure of the cortex, its specific areas, and its map-making abilities. Describes some of the recent discoveries about brain operation, development and functioning. (TW)

Argues against the theory of hemispheric dominance and discusses the dangers of developing an educational system based on the false assumptions of two-brain theories. (SRT)

The review examines issues and research relating to the involvement of the central nervous system in reading disorders. Questions regarding subtypes, pre- and perinatal influences, genetics, sex differences, and early identification are briefly surveyed along with a summary of major research findings in neuropsychology and neurology. (Author)

Previous studies have indicated that nonhuman animals might have a capacity for episodic-like recall reflected in memory for "what" events that happened "where" and "when". These studies did not identify the brain structures that are critical to this capacity. Here we trained rats to remember single training episodes, each composed of a series of…

While neuropsychology relates the neural structures damaged in traumatic brain injury with their cognitive functions in daily life, this report reviews evidence that elementary operations of cognition as defined by cognitive studies are the level at which the brain localizes its computations. Orienting of visual attention is used as a model task.…

The author cites the existence of parallel brain and mind growth spurts (phrenoblysis) in the periods 2-4, 6-8, 10-12, and 14-16 years, and suggests that early intervention programs for retarded children should be based on periods of greatest brain growth. (CL)

The paper deals with the effects of general experiences and specific educational practices on the structure and functioning of the central nervous system. (CL)

The article discusses neuropsychological and treatment aspects of brain behavior disorders in children from the standpoint of terms such as minimal brain dysfunction, learning disabilities, hyperactivity, and hyperkinetic syndrome. (Author/DLS)

Describes the use of brain models to connect the microscopic level accessible by molecular and cellular techniques with the systems level accessible by the study of behavior. Discusses classes of brain models, and specific examples of such models. Evaluates the strengths and weaknesses of using brain modelling to understand human brain function.…