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Van Houtven, Courtney Harold; Thorpe, Joshua M.; Chestnutt, Deborah; Molloy, Margory; Boling, John C.; Davis, Linda Lindsey – Gerontologist, 2013
Purpose of the Study: This paper is a report of a study of the Assistance, Support, and Self-health Initiated through Skill Training (ASSIST) randomized control trial. The aim of this paper is to understand whether participating in ASSIST significantly changed the out-of-pocket (OOP) costs for family caregivers of Alzheimer's disease (AD) or…
Descriptors: Intervention, Well Being, Alzheimers Disease, Expenditures
Nosofsky, Robert M.; Denton, Stephen E.; Zaki, Safa R.; Murphy-Knudsen, Anne F.; Unverzagt, Frederick W. – Journal of Experimental Psychology: Learning, Memory, and Cognition, 2012
Studies of incidental category learning support the hypothesis of an implicit prototype-extraction system that is distinct from explicit memory (Smith, 2008). In those studies, patients with explicit-memory impairments due to damage to the medial-temporal lobe performed normally in implicit categorization tasks (Bozoki, Grossman, & Smith, 2006;…
Descriptors: Alzheimers Disease, Classification, Patients, Short Term Memory
Brainerd, C. J.; Reyna, V. F.; Gomes, C. F. A.; Kenney, A. E.; Gross, C. J.; Taub, E. S.; Spreng, R. N. – Journal of Experimental Psychology: Learning, Memory, and Cognition, 2014
Advances in dual-retrieval models of recall make it possible to use clinical data to test theoretical hypotheses about mild cognitive impairment (MCI) and Alzheimer's dementia (AD), the most common forms of neurocognitive impairment. Hypotheses about the nature of the episodic memory declines in these diseases, about decline versus sparing of…
Descriptors: Neurological Impairments, Recall (Psychology), Memory, Alzheimers Disease
Ruparelia, Aarti; Pearn, Matthew L.; Mobley, William C. – Developmental Disabilities Research Reviews, 2013
Down syndrome (DS) is one of many causes of intellectual disability (ID), others including but not limited to, fetal alcohol syndrome, Fragile X syndrome, Rett syndrome, Williams syndrome, hypoxia, and infection. Down syndrome is characterized by a number of neurobiological problems resulting in learning and memory deficits and early onset…
Descriptors: Aging (Individuals), Older Adults, Mental Retardation, Down Syndrome
Pakhomov, Serguei V. S.; Hemmy, Laura S.; Lim, Kelvin O. – Neuropsychologia, 2012
The objective of our study is to introduce a fully automated, computational linguistic technique to quantify semantic relations between words generated on a standard semantic verbal fluency test and to determine its cognitive and clinical correlates. Cognitive differences between patients with Alzheimer's disease and mild cognitive impairment are…
Descriptors: Semantics, Alzheimers Disease, Diseases, Patients
Sannino, Sara; Russo, Fabio; Torromino, Giulia; Pendolino, Valentina; Calabresi, Paolo; De Leonibus, Elvira – Learning & Memory, 2012
The dorsal hippocampus is crucial for mammalian spatial memory, but its exact role in item memory is still hotly debated. Recent evidence in humans suggested that the hippocampus might be selectively involved in item short-term memory to deal with an increasing memory load. In this study, we sought to test this hypothesis. To this aim we developed…
Descriptors: Evidence, Animals, Schizophrenia, Alzheimers Disease
Perri, R.; Zannino, G. D.; Caltagirone, C.; Carlesimo, G. A. – Neuropsychologia, 2011
Semantic priming paradigms have been used to investigate semantic knowledge in patients with Alzheimer's disease (AD). While priming effects produced by prime-target pairs with associative relatedness reflect processes at both lexical and semantic levels, priming effects produced by words that are semantically related but not associated should…
Descriptors: Priming, Semantics, Alzheimers Disease, Diseases
Cuetos, Fernando; Samartino, Tamara; Ellis, Andrew W. – Psicologica: International Journal of Methodology and Experimental Psychology, 2012
Age of acquisition is possibly the single most potent variable affecting lexical access. It is also a variable that determines the retention or loss of words in patients who have suffered brain injury, and in patients with Alzheimer's disease. But the norms of age of acquisition currently available have largely been obtained from university…
Descriptors: Alzheimers Disease, Diseases, Young Adults, Older Adults
McKee, Ann C.; Stein, Thor D.; Nowinski, Christopher J.; Stern, Robert A.; Daneshvar, Daniel H.; Alvarez, Victor E.; Lee, Hyo-Soon; Hall, Garth; Wojtowicz, Sydney M.; Baugh, Christine M.; Riley, David O.; Kubilus, Caroline A.; Cormier, Kerry A.; Jacobs, Matthew A.; Martin, Brett R.; Abraham, Carmela R.; Ikezu, Tsuneya; Reichard, Robert Ross; Wolozin, Benjamin L.; Budson, Andrew E.; Goldstein, Lee E.; Kowall, Neil W.; Cantu, Robert C. – Brain, 2013
Chronic traumatic encephalopathy is a progressive tauopathy that occurs as a consequence of repetitive mild traumatic brain injury. We analysed post-mortem brains obtained from a cohort of 85 subjects with histories of repetitive mild traumatic brain injury and found evidence of chronic traumatic encephalopathy in 68 subjects: all males, ranging…
Descriptors: Neurological Impairments, Head Injuries, Chronic Illness, Brain
Plancher, G.; Tirard, A.; Gyselinck, V.; Nicolas, S.; Piolino, P. – Neuropsychologia, 2012
Most neuropsychological assessments of episodic memory bear little similarity to the events that patients actually experience as memories in daily life. The first aim of this study was to use a virtual environment to characterize episodic memory profiles in an ecological fashion, which includes memory for central and perceptual details,…
Descriptors: Computer Simulation, Alzheimers Disease, Diseases, Identification
Herrera, C.; Chambon, C.; Michel, B. F.; Paban, V.; Alescio-Lautier, B. – Neuropsychologia, 2012
Considering the high risk for individuals with amnestic Mild Cognitive Impairment (A-MCI) to progress towards Alzheimer's disease (AD), we investigated the efficacy of a non-pharmacological intervention, that is, cognitive training that could reduce cognitive difficulties and delay the cognitive decline. For this, we evaluated the efficacy of a…
Descriptors: Control Groups, Investigations, Intervention, Alzheimers Disease
Morelli, Claudia A.; Altmann, Lori J. P.; Kendall, Diane; Fischler, Ira; Heilman, Kennneth M. – Journal of Communication Disorders, 2011
Purpose: Individuals with probable Alzheimer disease (pAD) are frequently impaired at picture naming. This study examined whether a semantic elaboration task would facilitate naming in pAD, and whether training either semantically typical or atypical stimulus items facilitated generalized improvement in picture naming and category generation…
Descriptors: Semantics, Alzheimers Disease, Pictorial Stimuli, Recognition (Psychology)
Kuczera, Tanja; Stilling, Roman Manuel; Hsia, Hung-En; Bahari-Javan, Sanaz; Irniger, Stefan; Nasmyth, Kim; Sananbenesi, Farahnaz; Fischer, Andre – Learning & Memory, 2011
Learning and memory processes critically involve the orchestrated regulation of de novo protein synthesis. On the other hand it has become clear that regulated protein degradation also plays a major role in neuronal plasticity and learning behavior. One of the key pathways mediating protein degradation is proteosomal protein destruction. The…
Descriptors: Animals, Posttraumatic Stress Disorder, Alzheimers Disease, Diseases
Gollan, Tamar H.; Salmon, David P.; Montoya, Rosa I.; Galasko, Douglas R. – Neuropsychologia, 2011
The current study investigated the relationship between bilingual language proficiency and onset of probable Alzheimer's disease (AD) in 44 Spanish-English bilinguals at the UCSD Alzheimer's Disease Research Center. Degree of bilingualism along a continuum was measured using Boston Naming Test (BNT) scores in each language. Higher degrees of…
Descriptors: Alzheimers Disease, Language Proficiency, Bilingualism, Predictor Variables
Schaal, David W. – Behavior Analyst, 2012
This article presents an introduction to "The Behavior-Analytic Origins of Constraint-Induced Movement Therapy: An Example of Behavioral Neurorehabilitation," by Edward Taub and his colleagues (Taub, 2012). Based on extensive experimentation with animal models of peripheral nerve injury, Taub and colleagues have created an approach to overcoming…
Descriptors: Injuries, Behavior Disorders, Therapy, Genetics