There is broad recognition that anchor institutions--universities, hospitals, and other locally embedded organizations--can leverage their economic and human resources to revitalize and empower distressed neighborhoods. In Milwaukee, five anchor institutions, including Marquette University, collaborated with residents, city officials, and other stakeholders to transform the seven neighborhoods surrounding their campuses. The Promoting Assets and Reducing Crime (PARC) initiative is an innovative, data-driven, and place-based model of community collaboration to address neighborhood challenges. Over the last 3 years, PARC has helped stimulate economic development, enhance housing stock, improve public safety, and strengthen neighborhood connections in the city's Near West Side. In this article, we detail how PARC was established, the role of the university in this multianchor partnership, and how the initiative PARC integrates data and community input to inform and evaluate its work. The PARC initiative demonstrates promise as an effective model of university engagement in neighborhood revitalization efforts.