The article addresses clinical, neurodevelopmental, and psychological experiences of pregnant parents to build the case for shifting therapeutic approaches to promote the earliest possible connections between parents and their infant. The article emphasizes the rationale for therapeutic interface with families in pregnancy as it relates to stress…

Prenatal maternal depression affects both mother and fetus with long-term implications for offspring vulnerability to psychopathology through alterations to brain development, stress physiology, negative emotionality, and cognitive control. This article reviews evidence for the negative impact of prenatal maternal depression on offspring…

When expectant mothers are exposed to traumatic events such as natural disasters, their children are at increased risk for developmental and behavioral problems. Many people believe that young children will not be impacted by the traumatic experiences that occur during and following disasters. Therefore, planning for the youngest children at the…

The last decade has seen an exponential increase in the use of illicit and prescription opioids during pregnancy. Opioid dependency during pregnancy increases the risks of obstetric complications for mothers and potential dangers for newborns during infancy and later in life. The mother-child dyad faces specific hurdles when it comes to getting…

Parental substance use disorders negatively impact a child's development both prenatally and postnatally. Caregivers struggling with substance use disorders, and Opioid Use Disorder in particular, often have difficulty accessing appropriate holistic clinical interventions and are at high risk of losing custody of their children due to abuse and…

Advances in understanding of the dynamic molecular interplay between DNA and its surrounding proteins suggest that epigenetic mechanisms are a critical link between early life experiences (e.g., prenatal stress, parent-offspring interactions) and long-term changes in brain and behavior. Although much of this evidence comes from animal studies,…

Substance use and alcohol abuse during pregnancy are significant public health concerns. Neonatal abstinence syndrome (NAS) is a withdrawal syndrome that infants exposed to opioids may experience in the first few days of life. For most infants with NAS, exposure to opioids occurs during pregnancy while they are fetuses. Similarly, prenatal alcohol…

During pregnancy, low-income women are at high risk for depression and posttraumatic stress disorder (PTSD), but they are unlikely to receive mental health services. As a follow-up to Narayan et al. (2017), we provide a detailed picture of pregnant women's mental health service (MHS) need versus utilization. Results suggested that the majority of…

This article reviews the research base on the development of prenatal attachment and profiles four programs that foster this essential prenatal relationship: CenteringPregnancy®, the Practical Resources for Effective Postpartum Parenting program (PREPP), Mindfulness-Based Childbirth and Parenting (MBCP), and Moms2B.

Despite growing concern about substance misuse in pregnancy and infants born substance-exposed, few programs have been developed that address the complex needs of this vulnerable population. This article describes the process of developing Project NESST® (Newborns Exposed to Substances: Support and Therapy), from needs assessment to program…

As U.S. infant mortality remains relatively unchanged and maternal mortality is rising, it is increasingly clear that service providers need to address many of the modifiable risks that determine birth outcomes prior to pregnancy. Health professionals have promoted preconception care for decades as a way to improve women's and infant's health. Yet…

The prenatal period represents an opportunity to buffer the intergenerational transmission of adversity through integrated, comprehensive perinatal health services for women experiencing high levels of adversity and clinical symptoms. This article presents preliminary descriptive data, drawn from an ongoing clinical research study, on prenatal…

There have been revolutionary advances in the last decade in researcher's understanding of the genesis of life course health from the critical formative experiences before birth. Even more striking are the factors in a mother's developmental and nutritional history and experience that shape her health, a healthy pregnancy and delivery, and the…