In this study the effectiveness of the continuing professional education programmes of the Centre of Vocational Training (KEK INE GSEE) of the Region of Central Greece was evaluated in relation to the professional development of the participants. The programmes evaluated were implemented between 2012 and 2018. The survey followed a mixed methodological approach. In the quantitative study, 52 graduates of these programmes completed a questionnaire. The questionnaires were provided electronically to participants by sending a relevant hyperlink to their emails. The qualitative study was conducted through a personal, semi-structured interview with the head of the KEK INE GSEE of the Region of Central Greece. The results showed the correlation of work progression with the evaluation of the effectiveness of the continuing vocational training programmes. Also, the trainees of KEK INE GSEE of Central Greece stated that they were more satisfied with the trainers, the organization of the programme and the curriculum and that they benefited the most from the expansion of knowledge-skills, consulting support and the utilization of knowledge and skills acquired.