The ability to extract structural information from a drawing of a molecule is key to being successful in organic chemistry. One source of difficulty for novices in interpreting structures is that hydrogens bound to carbon are represented implicitly in the often-used line-angle structures. Other representations that explicitly show hydrogens, such…

This article presents the integration of Tinkercad, a free online modeling program that allows students to model molecular genetic concepts, into the distance learning process. The students had the opportunity to learn molecular genetics in a fun and more efficient way in spite of the limitations of the COVID-19 lockdown, and, in this respect, it…

We have developed a guided-inquiry laboratory exercise in which students perform viscosity measurements to infer the structure of poly(vinyl alcohol) (PVA) in aqueous solution. The activity combines both experiments and modeling. In the experimental portion of the exercise, students measure the viscosity of several solutions of PVA with differing…

The use of molecular models in chemistry and biochemistry classes is very effective in helping students understand covalent bonds and the chemical structure of molecules. However, conventional molecular models cannot represent intermolecular interactions such as hydrogen bonds and electrostatic interactions. Herein, we describe 3D printed…

Understanding the general ideas and methods of detecting molecular structures is essential in high school chemistry. However, there is a need for more practical activities in teaching. A hands-on activity was designed in this study, which uses flexible foam balls and long sticks such as knitting needles to imitate how scientists construct the 3D…

The initial learning experience is a critical opportunity to support conceptual understanding of abstract STEM concepts. Although hands-on activities and physical three-dimensional models are beneficial, they are seldom utilized and are replaced increasingly by digital simulations and laboratory exercises presented on touchscreen tablet computers.…

The introduction of Computational Chemistry via "Molecular Modelling and Drug Design" course at undergraduate level has opened wide possibilities for students to expand their knowledge of quantum chemistry, organic reaction mechanisms, protein-ligand interactions, drug design, and probable "in vivo" behavior of drug candidates.…

Prospective preschool teachers (PPTs) need to have learning experiences with the practice of scientific modelling to be able to design appropriate lessons as teachers. In the literature on research in science education, scarce experiences of PPTs in scientific modelling can be found. This study aims to fill the knowledge gap about PPTs'…

Many approaches to teaching Newman projections and conformational manipulation rely on lecturing using only two-dimensional representations. While molecular models are recognized as useful learning tools, students are often left to figure out how to use them during the initial learning process. The availability of basic online molecular models…

The study diagnosed chemistry teacher trainees' difficulties in naming and writing structures of spiro and bicyclic compounds. The case study design was conducted in a constructivist environment to enhance chemistry teacher trainees' ability to construct, represent, and interpret the structural formulae of spiro and bicyclic compounds. Purposive…

In undergraduate chemistry curricula that include computational modeling, students may gain first-hand experience in both introductory and advanced applications of this technique. However, although students can be exposed to the predictive power of computational work, its capabilities are often limited to determining the intrinsic properties of…

Across science disciplines, light is a common tool for measuring, characterizing, and catalysing molecules and molecular processes. Despite the ubiquity of light-based tools, little research has been done to investigate how students understand light and light-matter interactions (LMI). This topic is typically first introduced in first-year…

Molecular representations that show chemical bonding are ubiquitous in general and organic chemistry. These help in communicating chemistry concepts that are fundamental to understanding "how" and "why" molecules interact. The goal of this dissertation work is to offer an evidence-based report on the affordances and limitations…

Modeling an inter-ring torsional profile of a simple2,2'-bithiophenemolecule has been used to illustrate the main concepts associated with basic molecular modeling within an introductory course in a master's degree on computational modeling. The methodology proposed in the activity has been used to guide and train the student along the classical…

Acid-base chemistry, and in particular the Lewis acid-base model, is foundational to understanding mechanistic ideas. This is due to the similarity in language chemists use to describe Lewis acid-base reactions and nucleophile-electrophile interactions. The development of artificial intelligence and machine learning technologies has led to the…