This research aims to examine the effect of integrating arts in a laboratory practice, concerning basic artistic stage, chemistry and art, dermocosmetics, and laboratory practice level dermocosmetics production, on the learning performance of students. The application process consisted of two stages, namely an experimental stage and an artistic stage. In the experimental stage, the students basically produced soap, shampoo, body fragrance, tonic, lotion, cream, disinfectant and cologne in collaboration. Within the scope of the artistic stage, the students decorated the products they produced in the experimental stage using visual art and handcrafting techniques in an environment where they listened to classical music. They then created their own scenarios and recorded a short commercial to promote their products. The learning performances of the students were measured through a pre-/post-test of course content. At the end of the application process, it was concluded that the learning performance of the students improved, and the students provided positive feedback expressing that the application was instructive, reinforcing and entertaining and gave them the opportunity to develop a perspective toward art.