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Lugo, Joaquin N.; Smith, Gregory D.; Morrison, Jessica B.; White, Jessika – Learning & Memory, 2013
The phosphatase and tensin homolog detected on chromosome 10 (PTEN) gene product modulates activation of the phosphatidylinositol 3-kinase (PI3K)/AKT pathway. The PI3K pathway has been found to be involved in the regulation of the fragile X mental retardation protein, which is important for long-term depression and in the formation of new…
Descriptors: Fear, Conditioning, Mental Retardation, Genetic Disorders