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Bodfish, James W.; And Others – American Journal on Mental Retardation, 1997
Akathisia, a state of uncontrollable motor restlessness, is a side effect of neuroleptic treatment. The prevalence rate of akathisia in 94 adults with mental retardation was estimated to be 5% in neuroleptic-free subjects, 17% in neuroleptic-maintenance subjects, and 25% in neuroleptic-reduction subjects. Akathisia was also related to dyskinesia…
Descriptors: Adults, Drug Therapy, Incidence, Mental Retardation
Peer reviewedVadney, V.; And Others – Mental Retardation, 1994
This study evaluated effects on 77 institutionalized patients with mental retardation of changing from anticonvulsant Depakote to the similar drug, Depakene. Results showed no changes in seizure control, less lethargy on Depakene, but some increase in diarrhea and some changes in psychiatric symptoms. Substantial cost savings were achieved by the…
Descriptors: Cost Effectiveness, Drug Therapy, Institutionalized Persons, Mental Retardation
Peer reviewedSmalley, Susan L.; And Others – Journal of Autism and Developmental Disorders, 1992
A literature review of autism and tuberous sclerosis complex (TSC) substantiates a significant association between the two. Studies of 14 autistic probands and 13 TSC probands identified 7 TSC subjects with autism, who had more seizures and mental retardation than those without autism. More male TSC probands with autism than female were…
Descriptors: Autism, Correlation, Genetics, Heredity
Kastner, Ted; And Others – American Journal on Mental Retardation, 1992
This study of 40 patients with mental retardation receiving carbamazepine found hyponatremia in only 5 percent of these patients and found a statistically, but not clinically, significant decrease in serum sodium levels in patients receiving anticonvulsant polytherapy. Results support the use of this drug with patients with mental retardation and…
Descriptors: Drug Therapy, Medical Evaluation, Mental Disorders, Mental Retardation
van Emmerik, R. E. A.; And Others – American Journal on Mental Retardation, 1993
The arm tremor of adults (n=32) diagnosed as having mental retardation and/or tardive dyskinesia was examined through an analysis of the acceleration properties of several arm postures. The degree of arm acceleration was increased in all subjects compared to a control group without mental retardation. Effects of neuroleptic medication were noted.…
Descriptors: Adults, Drug Therapy, Human Posture, Mental Retardation
Peer reviewedWilliamson, David A.; Bolton, Patrick – Journal of Autism and Developmental Disorders, 1995
This report describes a sibling pair (ages 21 and 18), both with tuberous sclerosis. One sibling has atypical autism (but no mental retardation or seizure disorder) and the other has a seizure disorder but no autism or mental retardation. Both siblings had multiple bilateral brain lesions. Clinical findings are discussed in relationship to the…
Descriptors: Autism, Clinical Diagnosis, Medical Evaluation, Mental Retardation
Holmes, Gregory L.; And Others – American Journal on Mental Retardation, 1989
Five responses to Alvarez (EC 220 238) comment on discontinuation of antiepileptic drugs with mentally retarded patients. (DB)
Descriptors: Adults, Drug Therapy, Epilepsy, Followup Studies
Friedman, Debra L.; And Others – American Journal on Mental Retardation, 1992
This study with 65 individuals with mental retardation and additional seizure and/or psychiatric or behavioral disorders found that 9.2 percent experienced medication (carbamazepine) side effects, ranging from irritability to mania. More side effects were experienced by individuals with behavioral or psychiatric disorders than by those with an…
Descriptors: Behavior Change, Behavior Disorders, Behavior Problems, Drug Therapy
