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Walker, David L.; Davis, Michael – Learning & Memory, 2008
Within the amygdala, most N-methyl-D-aspartic acid (NMDA) receptors consist of NR1 subunits in combination with either NR2A or NR2B subunits. Because the particular subunit composition greatly influences the receptors' properties, we investigated the contribution of both subtypes to fear conditioning and expression. To do so, we infused the…
Descriptors: Learning Processes, Memory, Conditioning, Fear
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Ressler, Kerry J.; Rattiner, Lisa M.; Davis, Michael – Learning & Memory, 2004
Brain-derived neurotrophic factor (BDNF) has been implicated as a molecular mediator of learning and memory. The BDNF gene contains four differentially regulated promoters that generate four distinct mRNA transcripts, each containing a unique noncoding 5[prime]-exon and a common 3[prime]-coding exon. This study describes novel evidence for the…
Descriptors: Fear, Learning Processes, Brain, Neurology