Background: The National Institutes of Health (NIH) announced a revised, expanded definition of 'clinical trial' in 2014 to improve trial identification and administrative compliance. Some stakeholders voiced concerns that the policy added administrative burden potentially slowing research progress. Methods: This quasi-experimental study examined…

The aim of this study is to profile academic institutions (n = 127) based on publications, citations in the top 10% of journals, patent citations in Food and Drug Administration (FDA) approvals, clinical trials with uploaded results, contributions to clinical practice guidelines, awarded patents, start-ups, and licenses generating income in…

This study explores the views and experiences of knowledge translation of 14 Australian public health academics. Capacity to engage in knowledge translation is influenced by factors within the academic context and the interaction of the academic and policy environments. Early and mid-career researchers reported a different set of experiences and…

The last 20 years have seen significant international shifts towards greater patient and public involvement (PPI) in health research and development (R and D). In England, then first health R and D strategy in 1991 did not mention PPI. Twenty years later, PPI is deeply embedded within the National Institute for Health Research. This article…

These are interesting days in the scientific, social, and political debates about human embryonic stem cell research. Pluripotent stem cells--cells that can, in principle, give rise to the body's full range of cell types--were previously derivable only from human embryos that were destroyed in the process. Now, a variety of somatic cell types can…

Benjamin Moore (1867-1922), physiologist and biochemist, was an eminent member of the British scientific and medical community in the early twentieth century. As a founder and president of the State Medical Services Association (SMSA) from its establishment in 1912 until his untimely death in 1922, Moore was a prominent medical services activist…

Universities have much to contribute to the improvement of health delivery, research, and teaching/learning. In progressing health reform, the Government should be mindful of the need to: (1) strengthen high quality medical research; (2) promote translation of research to teaching, population health and health services; and (3) address Health…

The forensic use of Deoxyribonucleic Acid (DNA) is demonstrating significant success as a crime-solving tool. However, numerous concerns have been raised regarding the potential for DNA use to contravene cultural, ethical, and legal codes. In this article the expectations and level of knowledge of the New Zealand public of the DNA data-bank and…

Following the UN Millennium Summit in 2000, the Millennium Development Goals (MDGs) set global sector specific development targets to be achieved by the year 2015. In this article, the author explores the role of health and education research in producing technological innovations and global policy options and goals, such as the MDGs. Here, she…

Author described the tremendous advances that have been made in medical education, and the delivery of medical care to a huge and widely dispersed population. (Editor/RK)

Examines the lack of support for the training and employment of clinical investigators to capitalize on the knowledge gleaned from decades of basic scientific research. Argues that this dilemma can be addressed by carefully defining and marshalling a coalition of institutions to support increased funding for clinical investigations. (MDM)

Lessons learned from experience about shaping science policy include (1) the partnership between health and science interests is fundamental; (2) research fund allocation should be based on scientific merit; (3) better data and careful analysis are vital to decision making; and (4) policy principles should be clear and concise. (Author/MSE)

Despite key changes in the federal Acquired Immune Deficiency Syndrome (AIDS) research program, activists and some scientists are frustrated that not enough has been done and the actions taken have not had sufficient impact on the problem. Controversy over basic vs. clinical-trial research persists. (MSE)

The scientific community's expectations for biomedical research exceed funding capacity. Despite national social and economic problems, funding for biomedical research is already high. Additional funds will not solve the problem entirely. The biomedical community must set priorities and allocate money accordingly. New policies for allocating funds…

Summarizes and comments on three presentations relative to the life sciences and medicine given at the October 1995 working symposium of the Project on Conflict of Interest in University-Industry Research Relationships and included in this issue. Discusses the work of medical researcher David Blumenthal, political scientist Mark Frankel, and…