Evaluated were antibody responses to a potent protein antigen biophage ox 174 in 17 institutionalized Down Syndrome adolescents and six mentally retarded control Ss with normal karotype. (CL)

Examined were 55 children with adenosine deaminase enzyme deficiency and combined immunodeficiency disease, characterized by severe infections in early life. (CL)

Serum of five children ages 1 to 19 months with congenital pure red cell aplasia (incomplete or defective development of red blood cells) was injected in normal mice to determine possible inhibition of red blood cell formulating stimulants. (CL)

Examined for malignant hyperpyrexia (extremely high fever) were serum creatine phosphokinase (enzyme) levels of 27 children from 1-to 17-years-old with Noonan syndrome which is characterized by webbed neck, short stature and low set ears. (CL)

In an attempt to improve the identification of the asymptomatic carrier of classic phenylketonuria (PKU) 59 male and female normal control Ss were differentiated from 18 males and females heterozgous for PKU. (DB)

Studied were three unrelated infants with distal renal tubular acidosis (a condition characterized by an inability to acidify the urine to minimal pH levels resulting in the loss of bicarbonates). (DB)

Prenatal monitoring for metachromatic leukodystrophy (a fatal inherited metabolic disorder) suggested that the determination of levels of cerebroside sulfatase in the amniotic fluid helped in the prenatal detection of this disorder. (DB)

Investigated in 16 persons ages 3 to 23 years with severe cystic fibrosis was the absorption level of digoxin (a lipid soluble medication). (CL)

Examined were eight patients with cerebro-hepato-renal syndrome of Zellweger (associated with severe cerebral dysfunction, hypotonia and unusual appearance). (CL)