Evaluated by radiography was tongue size relative to the mouth cavity in eight children from 5 to 15 years of age with Down's syndrome. (DB)

Analyzed were serum levels of IgA, IgG, ad IgM in groups of institutionalized and noninstitutionalized Down's syndrome subjects and in institutionalized retarded children with other etiologies. (KW)

Levels of serum IgE (an immunoglobulin carrying reaginic antibody activity) were investigated in 16 Down's syndrome adolescents (12-to 18-years old) and in an equal number of retardates matched for age and sex residing in the same institution. (CL)

Banding techniques were used in follow-up chromosome studies on two adult institutionalized retardates who had been previously described as having a low ridge count due to a high number of arches on the fingertips associated with undefined chromosomal abnormalities. (CL)

Post mortem examinations were done on two adult siblings (one female and one male) who had been clinically described as suffering from mental handicap, deaf mutism, ataxia, hypogonadism, and hormonal disorders. (DB)

Reported was the medical case history of a young man with Smith-Lemli-Opitz syndrome of mental deficiency with characteristic physical features. (CB)

Urine samples of 668 Swedish children with progressive psycho-motor retardation, coarse facies, and, in some cases, skeletal changes and vacuolated lymphocytes, were examined by means of high voltage paper electrophoresis. (DB)

In the first of two reports, two typical cases of Jadassohn's Naevus Phakomatosis (JNPh-a syndrome composed of a characteristic skin naevus, mental retardation and epilepsy, as well as various congenital abnormalities) are reported, with full clinical details, history, and the results of the investigation. (Author)

Reported was the medical case history of an 11-year-old profoundly retarded boy in which his micropolygyric frontal cortex was found to reveal three chemical changes. (CB)