The dissolution of cobalt­(II) chloride in an appropriate binary alcohol solvent yields an equilibrium mixture, consisting of the differently colored octahedral (pink in color) and tetrahedral (blue in color) cobalt­(II) coordination complexes, which can exhibit a brilliant and reversible pink-to-blue color transition over a ~10 °C window - i.e.,…

For educational institutions in science, technology, engineering and mathematics (STEM) areas, the provision of practical learning scenarios is, traditionally, a major concern. In the 21st century, the explosion of information and communication technology (ICTs), as well as the universalization of low-cost hardware, has allowed the proliferation…

A major challenge when designing new experiments for the general chemistry laboratory is introducing students to the necessary techniques while keeping the experiment engaging and accessible. This work presents a new multiweek activity designed to introduce students to advanced instrumentation in the form of high-performance liquid chromatography…

Organizing undergraduates in chemistry, energy engineering, and chemical engineering specialties to participate in an energy transformation experiment can encourage them to think about the impact of human activities on nature and stimulate them to learn more about the topic. This laboratory experiment demonstrates a general approach to the…

Lateral flow assays play a key role in mass testing for COVID-19, for example, in schools. The red color of the detection lines is caused by gold nanoparticles that are conjugated to antibodies. Hence, these tests present a very topical learning opportunity in the emerging field of nanoscience. To highlight the role of gold nanoparticles, a…

A new undergraduate organic laboratory experiment has been developed and implemented for the Ugi three-component synthesis of the topical anesthetic lidocaine with excellent atom economy. Paraformaldehyde, diethylamine, and 2,6-dimethylphenyl isocyanide were combined and conveniently stirred at room temperature for a week in methanol with acetic…

Mercury beating heart (MBH) is a well-known demonstration of redox processes. However, the development and application of the MBH system are significantly restricted due to its safety issues. Here, a direct current electric field-enabled gallium-based liquid metal heartbeat in a salt solution or alkaline solution is introduced as a demonstration…

Undergraduate organic chemistry laboratory courses act as a baseline for introductory scientific experimentation. These courses provide students with the knowledge and skills for their future careers. The traditional lab is conducted by providing a structured protocol of the experiment for the students to follow and reproduce the assigned task…

A new undergraduate organic laboratory experiment has been developed for amide bond formation between biorenewable 2-furoic acid and either of two substituted piperazines to prepare medicinally relevant amide products using a procedure with industrial significance. The reactions proceeded smoothly under ambient conditions using the combination of…

A laboratory experiment was performed using tetra-n-butylammonium bromide (TBAB) ionic semiclathrate hydrate, a crystalline compound. Ionic semiclathrate hydrates have unique properties, and hence, novel technologies utilizing the ionic semiclathrate hydrates have been proposed to date. Thus, students could learn fundamentals of functional…

A laboratory experiment was developed to introduce undergraduate chemistry students to the chemical characterization of agroindustrial waste extracts by gas chromatography-mass spectrometry (GC--MS). The students prepared hexane and dichloromethane extracts from black pepper ("Piper nigrum" L.) waste. GC--MS analysis revealed the…

Artificial intelligence (AI) is receiving a lot of attention in various fields. There is a need for educating students in AI technology. In this context, we have created a new type of carbon dioxide fountain by integrating AI with the well-established Arduino-carbon dioxide fountain experiment. This experiment consists of an Arduino…

A handheld refractometer (HHR) is a versatile instrument in the chemistry lab or in the workplace. It is also inexpensive enough (<$25 U.S.) that all students in a chemistry lab can have one or students completing laboratories remotely can purchase one. We report four applications of two different HHRs: one HHR for which the scale reads…

This experimental lab set is for students taking college chemistry courses. It includes four laboratory works and completely illustrates the important parts of chemical kinetics, namely the determination of the rate constant and the determination of the factors influencing its value. They can be used in a laboratory set for a physical chemistry…

In an effort to further develop critical thinking and problem solving skills, a guided-inquiry-based, multioutcome organic chemistry synthesis and characterization experiment was developed. Students were provided with the protocol for a time-saving microwave-assisted acetanilide synthesis reaction from acetic anhydride and an unknown primary aryl…