The importance of generic skills for life scientists is commonly recognised by employers, graduates, and higher education institutes. As it remains unclear which generic skills are relevant for different life sciences career paths, this study aims to give an overview to inform and inspire universities and students, by analysing 179 Dutch entry-level job postings. We deductively coded nine career paths, namely: life sciences industry, PhD-student, quality compliance, research-related, sales & business, communication/education, information technology, consultancy, and policy. We coded generic skills using an adapted categorisation consisting of 46 generic skills within four categories, which were: self, others, information, and tasks. The descriptive statistics and cluster analysis results showed that although language, communication, and collaboration were the most requested skills, differences in requested generic skills between career paths and cluster composition were observed as well. We concluded that although some generic skills are important in general, other generic skills are relevant for specific life sciences career paths. To educate skilled life scientists, universities should consider the flexible integration of these generic skills in their life sciences programmes.