Self-injurious behaviors (SIB) are elevated in autism spectrum disorder (ASD) and related genetic disorders, but the genetic and biological mechanisms that contribute to SIB in ASD are poorly understood. This study examined rates and predictors of SIB in 112 individuals with disruptive mutations to ASD-risk genes. Current SIB were reported in 30%…

Self-injury is common in autism spectrum disorder (ASD); however few studies have investigated correlates of self-injury or the putative associations with self-restraint. Questionnaire data on self-injury, self-restraint, health conditions, overactivity/impulsivity and repetitive/restricted behavior were collected on 208 children and 216 adults…

Objective: To assess the safety of meningococcal group B (MenB)-4C vaccine. Participants: Undergraduates, dormitory residents, and persons with high-risk medical conditions received the MenB-4C vaccine two-dose series during mass vaccination clinics from 12/2013 through 11/2014. Methods: Adverse events (AEs) were identified by 15 minutes of…

Research has suggested that individuals who engage in self-injurious behavior may have enhanced expressions of pain, which contradicts previous assertions of blunted pain sensitivity in this population. The purpose of this study was to measure expressions of pain among young children being evaluated for autism and other neurodevelopmental…

Our research sought to identify the most common movement patterns and postures performed by sign language interpreters and the frequency and severity of any pain that may be associated with the movements. A survey was developed and mailed to registered sign language interpreters throughout the state of Illinois. For each specific upper extremity…

Reports of injury/illness incidents involving 123 adults with developmental disabilities were studied to determine the incidence of pain insensitivity/indifference. A significantly elevated pain threshold was noted for 25% of subjects and was related to severity of mental retardation. Medical and rehabilitation implications in terms of risking…

A study assessed the frequency of self-reported hand/wrist problems among 184 sign-language communicators. Fifty-nine percent reported experiencing hand/wrist problems, 26 percent reported experiencing hand/wrist problems severe enough to limit their ability to work, and 18 percent reported a medical diagnosis of wrist tendinitis, carpal tunnel…

This study assessed occurrence and level of pain and injury history associated with powerlifting training in 11 adults with visual impairments. Powerlifting training was associated with an elevated occurrence of pain in shoulders, elbows, lower back, and knee regions. Injury rate, however, was lower than for athletes without visual impairments.…

Data were collected retrospectively from insurance information forms and histories of 111 patients (ages 14-84) referred to physical therapy for evaluation of back and/or neck pain. Analysis indicated that patients with compensable (work-related or motor vehicle accident) injuries infrequently acknowledged prior episodes of back or neck pain. (JDD)