This article introduces neurodevelopmental and clinical considerations for treating adolescents with co-occurring attention deficit hyperactivity disorder (ADHD) and adolescent substance use (ASU) in outpatient settings. We first describe neurobiological impairments common to ADHD and ASU, including comorbidity with conduct disorder, that evoke a…

Objective: Sexually or physically abused children are at risk for neurobiological dysregulation as well as for internalizing and disruptive behavior disorders. Stress-related autonomic nervous system (ANS) down-regulation has been proposed as a sequela of abuse and was investigated in the present study. Methods: Child Protective Services…

Neuropsychological functioning of 30 siblings of children with autism (AU-S), 28 siblings of children with mental retardation of (MR-S), and 30 siblings of children with developmental language delay (DLD-S) was compared. Two siblings, both AU-S, received diagnoses of pervasive developmental disorder (PDD). More siblings with cognitive disabilities…

Clinical and neurophysiological findings for 28 patients (mean age 15 years) with mental retardation, autism, and epilepsy were described, including classification of seizure type and epileptic syndrome, etiology, severity of autism and epilepsy, electroencephalography findings, and neuroimaging findings. No particular epileptic syndrome…

This fact sheet uses a question-and-answer format to summarize what is known about Prader-Willi Syndrome (PWS), a complex genetic disorder resulting in short stature, mental retardation or learning disabilities, incomplete sexual development, characteristic behavior problems, low muscle tone, and an involuntary urge to eat constantly, which…

This monograph describes community rehabilitation services available to persons with traumatic brain injury in Israel. Following a foreword by Leonard Diller which cites the incidence of traumatic brain injury and notes existing intervention models, an introductory chapter by Shlomo Katz and Victor Florian provides a historical survey of the…

This study evaluated 102 patients (ages 5 to 13) at the Medical University of South Carolina's Pediatric Neurology Clinic for incidence of psychiatric or language disorders. Parents completed the Pediatric Symptom Checklist (PSC), the Child Behavior Checklist, and the Language Problems Scale; phone interviews were conducted to determine child…

This report, arising from a 1991 meeting, provides an update to two of the six areas covered in the 1989 long-term plan of the National Institute on Deafness and Other Communication Disorders. These include: (1) balance and the vestibular system; and (2) language and language impairments. For each area, the state of the art is reviewed, recent…

Background: Hans Asperger drew attention to individuals who show the core symptoms of autism in the presence of high verbal intelligence. Methods: A review of the literature explores current issues concerning the diagnosis and nature of Asperger syndrome. Results: The behavioural and neurophysiological evidence to date suggests that Asperger…

This report on the state of the science in autism contains responses to questions posed by the National Institutes of Health (NIH) and recommendations concerning diagnosis, epidemiology, pathophysiology, communication/social/emotional development, medical intervention, social and behavioral intervention, and biostatistics. General recommendations…

The report to Congress by the Interagency Committee on Learning Disabilities, required by the Health Research Extension Act of 1985, Public Law 99-158, provides a review and assessment of Federal research priorities, activities, and findings regarding learning disabilities. Included in the report is information on (1) the number of persons…

The proceedings include 33 papers and two addresses on the psychopathology of mental development. The following six subject areas are considered: genetics and neurophysiology, socio-cultural and paranatal factors; epidemiology; behavior characteristics and learning; observational techniques and measurement of intelligence; and diagnosis and…