The essence of higher education is to cultivate innovative talents for the society. Hence, higher education institutions (HEIs), on the one hand, need to respond to social needs and government policies. On the other hand, they need to keep pace with the times and improve the details of teaching to improve the effectiveness of education. In this paper, several combination education examples in HEIs about safety education and innovation education are shown to encourage students to realize innovations in technique during their laboratory experiments on electrospinning. To obtain professional knowledge and traditional professional skills, students are taught to implement electrospinning, an advanced technique for treating polymers, in the research laboratory. Safety education is also taught, during which the students are encouraged to play their subjective roles and ponder on how to apply innovations for safe, effective, and innovative implementation. The students apply a series of small technological innovations for the spinneret, which is the most innovative part of an electrospinning system. They can modify the spinneret for safer, more energy-saving, and more convenient operations of the single-fluid blending, coaxial, triaxial, and side-by-side electrospinning processes. Moreover, the innovations can deepen their professional knowledge of electrospinning and stimulate their enjoyment of innovations. Safety education on electrospinning can be a powerful tool for promoting technological innovations in students and increasing their awareness of related safety issues. The reported protocols in this paper show a new way for conducting combined education in HEIs on advanced techniques.