Arguments about the role of basic science courses in a pharmacy curriculum moving toward additional clinical instruction center around semantics, value judgments, and philosophy. Drug analysis can, however, provide a valuable service in the areas of drug detection and monitoring. (Author/LBH)

An experimental exercise on analytical proficiency studies in collaborative trials is proposed. This practical provides students in advanced undergraduate courses in chemistry, pharmacy, and biochemistry, with the opportunity to improve their quality assurance skills. It involves an environmental analysis, determining the concentration of a…

Outlines advances in the microbial production of pharmaceuticals, including the manufacture of penicillin and other antibiotics, vitamins, hormones, alkaloids, antitumor drugs, and interferons. (CS)

Compares traditional and newer methods by which microorganisms are used to produce industrial chemicals. Includes a discussion of economic considerations and new genetic methods in programing microorganisms. Details methods for producing enzymes, aliphatic organic compounds, amino acids, ethanol, n-butanol, and alkene oxides. (CS)

In a summer faculty development workshop, seven faculty in different pharmacy disciplines (biochemistry, therapeutics, pharmacy management, pharmaceutics, pathophysiology, pharmaceutical analysis, pharmacy administration) clarified critical thinking objectives for their courses, practiced this approach in a faculty workshop, and piloted the…

Presents an overview of the field of industrial microbiology, providing historical backgrounds of scientific discoveries in the field and descriptions of industrially important microorganisms. Applied research in industry is also detailed, with mention of gene amplification, DNA recombination, pharmaceutical approaches, and detoxification and…

Traces the development of the field of industrial microbial genetics, describing a range of techniques for genetic programing. Includes a discussion of site-directed mutagenesis, protoplast fusion, and recombinant DNA manipulations. (CS)

Describes industrially important yeasts, molds, bacteria, and actinomycetes. Discussed in detail are microbial products, such as primary metabolites, secondary metabolites, enzymes, and capsular polysaccharides. Traces the historical background of human cell culture, mentioning recombinant DNA research and hybridization of normal mammalian cells…

In view of increased public demand since 1965 for medical curriculum re-evaluation, the Duke University School of Medicine offered the first new model of medical education responsive to social pressures for change. The new Duke curriculum included presentation by each basic science department of the core of principles and information considered…