Reported is a study of the activities and performance of institutional review boards to protect human research subjects. Institutional review boards had some direct impact on half of the proposals reviewed. The data raised questions about the effectiveness of some review board action. (Author/MP)

Defines meta-analysis as statistical procedures for combining results from previous separate studies. Discusses four charges promoted by some skeptics as it relates to this statistical procedure. States that many of the trends making a place for meta-analysis are disturbing. (RT)

Discusses competing grant applications both new and renewal, including those for traditional grants (research projects initiated and conducted by individual investigators) and those for program project grants which support multidisciplinary efforts of a relatively large group of investigators. (Author/DS)

Described is an ongoing study of monozygotic and dizygotic twins, separated in infancy and reared apart. Discussed are the procedures and results of this study with interpretations of the results. The effects of parenting, education, and other interventions are considered. (CW)

Discussed is wavelet theory, which provides ways to rearrange data to reveal features of a physical or mathematical system which might otherwise be hidden. This theory is compared to fourier analysis and the advantages of wavelet theory are stressed. Applications of this technique are suggested. (CW)

Described is the role of technology in the Human Genome Project. A poster of the human genome as is known in 1990 is provided with a list of representative genes and a glossary of terms. (CW)