The guide presents information about ordering, using, storing, and maintaining chemicals in the high school laboratory. The guide also provides information about chemical waste, safety and emergency equipment, assessing chemical hazards, common safety symbols and signs, and fundamental resources relating to chemical safety, such as Material Safety Data Sheets and Chemical Hygiene Plans, to help create a safe environment for learning. In addition, checklists are provided for both teachers and students that highlight important information for working in the laboratory and identify hazards and safe work procedures. This guide is not intended to address all safety issues, but rather to provide basic information about important components of safety in the chemistry laboratory and to serve as a resource to locate further information. Appended to this guide are: (A) Common Safety Symbols; (B) National Fire Protection Association Hazard Labels; (C) Substances with Greater Hazardous Nature Than Educational Utility; (D) Substances with a Hazardous Nature, But May Have Potential Educational Utility; (E) Incompatible Chemicals; (F) Recommended Safety and Emergency Equipment for the Laboratory; (G) How Does a Chemical Enter the Body?; (H) What are Exposure Limits?; (I) General Guidelines to Follow in the Event of a Chemical Accident or Spill; (J) Understanding an MSDS; (K) Sample MSDS; (L) Web Site Resources; and (M) Glossary. The guide also contains pull-outs at the end of the document for easy copying for distribution or posting: Safety Do's and Don'ts for Students; How Should Chemicals Be Stored? and Suggested Shelf Storage Pattern. (Contains 1 table.)