Polymer chemistry is an important subject in the undergraduate chemistry curriculum. It is required for ACS-certified degrees and significantly connects to real world issues like the plastic waste crisis. While some concepts of polymer chemistry can be incorporated into lecture courses, students' understanding of material properties and…

The Making Introductory Courses Real while Online (MICRO) laboratory project was developed to meet the need for hands-on experiments, focused on topics in analytical chemistry, to be delivered safely remotely or in a socially distanced in-person lab. Unlike more traditional lab experiments, MICRO laboratories use only microgram or nanogram amounts…

In this guided-inquiry lesson, students were tasked with determining the efficacy of an at-home drinking water filter at removing lead (Pb) from tap water using graphite furnace atomic absorption spectroscopy by determining the concentration of lead before and after filtration. The lesson was structured to allow students to choose and perform…

Scientific laboratories are among the most challenging course components to integrate into online instruction. Available technology restricts the design and nature of experiments, and it can be hard to replicate the collaborative lab environment where frequent and immediate instructor feedback is the norm. Here we report on technological and…

Inquiry-based learning can be an effective approach when students are provided with sufficient guidance. However, there is an ongoing debate among practitioners about the nature, type, and level of such guidance. This study investigated the effects on middle school students' (N = 116) conceptual knowledge and inquiry skills acquisition of…

Lab-on-a-chip devices are a critical and emerging chemical technology. New pedagogical tactics that effectively capture both analytical chemistry concepts along with the design elements unique to these devices are necessary for effective integration in the undergraduate chemistry curriculum. This article develops a design-based learning laboratory…

Mass spectrometry is frequently introduced to undergraduate students as an instrument for both qualitative and quantitative chemical analysis. One of the most common uses of mass spectrometry (MS) is to deduce or confirm a compound's chemical formula, by relying on high-resolution accurate-mass measurements. However, like all forms of instrumental…

An inquiry-based learning approach was implemented into comprehensive organic chemistry experiments focusing on the formation process of N-phenylbenzamide from the reaction between N-benzylideneaniline and benzoyl peroxide in commercial dimethyl sulfoxide. Students conducted comparative experiments using alternative reagents or reaction conditions…

A high performance liquid chromatography (HPLC) experiment for the upper level analytical chemistry laboratory is described. The students consider the effect of mobile-phase composition and pH on the retention times of ionizable compounds in order to determine the acid dissociation constant, K[subscript a], of a phenolic acid. Results are analyzed…

Glycoscience continues to be an underrepresented topic in current undergraduate-biochemistry-laboratory curricula. Of the educational laboratories present in this subject area, few introduce students to cutting-edge methods and techniques related to carbohydrates. A multiweek series of experiments is described that highlights a recently published…

This two-part laboratory experiment is concerned with investigating key aspects of the Suzuki-- Miyaura cross-coupling reaction. The first part of this experiment utilizes high-throughput experimentation techniques to reinforce, explore, and extend fundamental concepts that are presented in the classroom. In contrast, the second part employs…

Under the new ABET accreditation framework, students are expected to demonstrate "an ability to develop and conduct appropriate experimentation, analyze and interpret data, and use engineering judgment to draw conclusions." Traditional, recipe-based labs provide few opportunities for students to engage in realistic experimental design or…

An undergraduate experiment for the organic laboratory is described that utilizes microwave heating to prepare 5- substituted 1H-tetrazole derivatives through a (3 + 2) cycloaddition between aryl nitriles and sodium azide. The reaction mixture is analyzed by thin layer chromatography. The products are purified through an acid-base extraction and…

The natural sciences, by their very nature, are based on the exploration of the physical world, and digital mobile devices are considered appropriate to support this exploration (Suárez et al., 2018) since they offer the tools that make this investigation more accessible but also ubiquitous (Crompton et al., 2017). Inquiry-based learning is a…

Students learned the principles and practice of photometry through project-based learning. They addressed the challenge of measuring the unknown concentration of a colored substance using a photometer they were required to design, build, and test. Then, they used that instrument to carry out the experiment and fulfill the challenge. A photometer…