Gene therapy has fascinated clinicians, scientists, and patients since decades ago because of its potential to treat a disease at the genetic level. This can be achieved in many ways, including replacing a disease-causing gene with a healthy copy. Gene therapy must overcome complex tissue and cellular barriers to introduce genetic modifications…

This article reviews the discovery of RNA interference, its mechanism of action and its functions, and the principles, challenges, and strategies for RNA therapeutics.

Learning about stem cells within the context of treating pet illness or injury is an additional way for teachers to discuss the integration of science, technology, and veterinary medicine. We explain how practitioners in veterinary medicine harvest animal stem cells from adipose (fat) tissue in treating pet illness or injury. Further, we narrate…

Using Pompe disease as a context affords the opportunity for students to consider multiple biological concepts and embraces the Next Generation Science Standards Disciplinary Core Ideas Structure and Function (LS1.A) and Inheritance of Traits (LS3.A) as well as Crosscutting Concepts Structure and Function and Cause and Effect. These crosscutting…

Translational research has proven to be a powerful process that bridges the gap between basic science and medical practice. The complexity of translational research is two-fold: integration of vast amount of information in disparate silos, and dissemination of discoveries to stakeholders with different interests. We designed and implemented a…