The laboratory practice "Primary culture and directional differentiation of rat bone marrow mesenchymal stem cells (BMSCs)" is part of a required course for sophomore medical students at Tongji university, which has been conducted since 2012. Blended learning has been widely applied in medical courses. Based on a student-centered…

The decoding of the human genome was supposed to have been the dawn of the age of personalized medicine. It turned out, though, that health is affected by a lot more than genes. As scientists were already aware, the environment and life experiences also have a huge impact on disease. Researchers, such as Jeremy K. Nicholson, have worked to make…

In an attempt to improve the identification of the asymptomatic carrier of classic phenylketonuria (PKU) 59 male and female normal control Ss were differentiated from 18 males and females heterozgous for PKU. (DB)

In departure from the standard approach of using several problems to cover specific topics in a class, I use a single problem to cover the contents of the entire semester-equivalent biochemistry classes. I have developed a problem-based service-learning (PBSL) problem on HIV/AIDS to cover nucleic acid concepts that are typically taught in the…

EIGHTY-FIVE BOOKS AND ARTICLES DEALING WITH DOWN'S SYNDROME (MONGOLISM) ARE LISTED. DATING FROM 1933 THROUGH 1965, THE ITEMS CITED FOCUS ON BIOCHEMICAL AND GENETIC FACTORS AS WELL AS THE DEVELOPMENT OF THE MONGOLOID CHILD. (JD)

There are two general categories (not necessarily mutually exclusive) of congenital defects: (1) abnormalities that have an hereditary basis, such as single and multiple genes, or chromosomal abberration; and (2) abnormalities that are caused by nonhereditary factors, such as malnutrition, maternal disease, radiation, infections, drugs, or…

Resulting from a 1-day conference on mongolism, the book contains research studies and discussion summaries. Papers include "Parental Age, Live-Birth Order, and Pregnancy-Free Interval in Down's Syndrome in Japan" by E. Matsunaga, "Consanguineous Marriages and Mongolism" by H. Foressman and H. O. Akesson, "Correlation of Dermal Patterns on…

In this report, emphasis is placed on major research developments in the reproductive sciences, their impact on the health of individuals as well as on that of society, and on current trends that may provide new opportunities for future research in fertility and infertility. In the first section, major developments in the reproductive sciences are…

Evidence today indicates that the causes of mental retardation are biological, psychological, and social in origin and that a combination of these causes frequently occur in a single individual. Mental retardation is identified clinically by the presence of several signs that include, but are not limited to, a significant impairment of…

DATA FROM RECENT COMPREHENSIVE STUDIES OF THE PATHOLOGY OF MENTAL RETARDATION ARE ASSEMBLED, INCLUDING MATERIAL ON ETIOLOGY, MORPHOLOGY, BIOCHEMISTRY, AND LABORATORY DIAGNOSIS. AREAS COVERED ARE (1) GENETIC CAUSES OF MENTAL RETARDATION, (2) DISORDERS OF GESTATION, (3) BIRTH INJURY, (4) GENERAL CONSIDERATIONS OF POSTNATAL CAUSES OF MENTAL…

A discussion of the incidence of epilepsy is followed by a discussion of etiology including the following causes: genetic and birth factors, infectious diseases, toxic factors, trauma or physical agents, heredofamilial and degenerative disorders, circulatory disturbances, metabolic and nutritional disturbances, and neoplasms. Epileptic seizures…

Part II of a two-part publication listing mental retardation grants awarded by the U.S. Department of Health, Education, and Welfare in fiscal year 1968 (July 1, 1967, to June 30, 1968), the text includes grants awarded in the areas of research and demonstration. (Part I covers grants in training and construction.) Grants are arranged according to…