Objective: We offer an overview of ADHD research using mouse models of nicotine exposure. Method: Nicotine exposure of C57BL/6 or Swiss Webster mice occurred during prenatal period only or during the prenatal and the preweaning periods. Behavioral, neuroanatomical and neurotransmitter assays were used to investigate neurobiological mechanisms of…

To test the hypothesis that social rearing may induce malleability, socially reared and socially isolated mallard duck, Anas platyrhynchos, embryos and hatchlings were exposed to the maternal call of a chicken, Gallus gallus domesticus, until 48 h after hatching. The hatchlings were then tested with the chicken call versus the mallard maternal…

Gilbert Gottlieb's formative role in establishing a science of experimental behavioral embryology is described. His experimental program on the development of species identification served as a model for developmental psychobiologists seeking alternatives to the nature-nurture dichotomies prevalent in the 20th century. Two of the major concepts…

The review examines the literature on the behaviorally teratogenic aspects of Fetal Alcohol Syndrome, including: (1) prevalence of alcohol abuse among women, (2) acute and chronic effects of alcohol on the fetus, (3) genetic susceptibility, (4) neuropathology, (5) correlative conditions, and (6) animal studies. (Author/DB)

Expression of the immediate-early genes (IEGs) has been shown to be induced by activity-dependent synaptic plasticity or behavioral training and is thought to play an important role in long-term memory. In the present study, we examined the induction and expression of the IEG-encoded protein Egr-1 during an in vitro neural correlate of eyeblink…