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Tan, Mei; Bowers, Megan; Thuma, Phil; Grigorenko, Elena L. – New Directions for Child and Adolescent Development, 2020
Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between 1 and 4 µg/mL, and neurological side effects at supratherapeutic levels, several investigations into the pharmacokinetics of the drug and its…
Descriptors: Drug Therapy, Outcomes of Treatment, Acquired Immunodeficiency Syndrome (AIDS), Neurology