This study examined how the intersection of burnout and resilience impacts academic medical centers' faculty since the COVID-19 pandemic. This study used convenience sampling to recruit faculty who self-identified as primarily clinician educators, clinicians, or undergraduate medical educators at academic medical centers or those affiliated with academic medical centers to achieve a sampling size of 2590 participants. The participants completed an online survey incorporating the Maslach Burnout Inventory and Resilience-14 instruments and demographic questions. A generalized linear model was used to examine the factors that impact burnout and resilience of academic faculty. The results of this study indicated undergraduate medical educators had the highest level of burnout. Unlike previous studies, the female gender did not significantly impact burnout scores but did impact resilience scores. Race was a significant predictor of burnout, in which those identifying as Native American/Hawaiian/Pacific Islander had the highest rates of burnout. Resilience, which is thought to be protective against burnout, was significantly higher in faculty who were considered late-career faculty. Most importantly, this study indicated burnout was higher in academic faculty after the COVID-19 pandemic than it was before. Furthermore, this study indicated that 75% of academic faculty suffered from emotional exhaustion (i.e., the most closely linked facet of burnout), which is significantly higher than currently reported levels of burnout of nonacademic clinicians and biomedical scientists. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://bibliotheek.ehb.be:2222/en-US/products/dissertations/individuals.shtml.]