In this article, we explore space, time, and mattering in relation to empathy and nature by examining videos created by 10 undergraduate education majors attending university in Helsinki. Completed as part of a cross-curricular project between art and music students, the video artworks were inspired by a garden theme. Using arts-based, postqualitative methods, we trace relationships or threads of interconnectedness between empathy and nature, viewing them as entangled "spacetimemattering" events. Working in the intersection of arts and sciences, and inspired by new materialisms--specifically Karen Barad's theory of agential realism--we rethink space and time in artmaking as spacetimemattering. Spacetimemattering, understood as a unified concept, reveals how artistic practices work to conjure heterogeneous understandings of empathy, involving more-than-human objects/materials/matter as entangled phenomena that transcend Cartesian dualisms. In concluding, we discuss implications as to why rethinking space and time as spacetimemattering is important for future art education and research practices.