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Park, Chun Hui J.; Ganella, Despina E.; Kim, Jee Hyun – Learning & Memory, 2017
Anxiety disorders emerge early, and girls are significantly more likely to develop anxiety compared to boys. However, sex differences in fear during development are poorly understood. Therefore, we investigated juvenile male and female rats in the relapse behaviors following extinction of conditioned fear. In all experiments, 18-d-old rats first…
Descriptors: Animals, Anxiety Disorders, Gender Differences, Fear
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Bisby, Madelyne A.; Baker, Kathryn D.; Richardson, Rick – Learning & Memory, 2018
NMDA receptors (NMDARs) are considered critical for the consolidation of extinction but recent work challenges this assumption. Namely, NMDARs are not required for extinction retention in infant rats as well as when extinction training occurs for a second time (i.e., reextinction) in adult rats. In this study, a possible third instance of…
Descriptors: Fear, Learning Processes, Conditioning, Brain