NotesFAQContact Us
Collection
Advanced
Search Tips
Showing all 5 results Save | Export
Fibroblast Growth Factor-2 Alters the Nature of Extinction
Peer reviewed Peer reviewed
Direct linkDirect link
Graham, Bronwyn M.; Richardson, Rick – Learning & Memory, 2011
These experiments examined the effects of the NMDA-receptor (NMDAr) antagonist MK801 on reacquisition and re-extinction of a conditioned fear that had been previously extinguished before injection of fibroblast growth factor-2 (FGF2) or vehicle. Recent findings have shown that relearning and re-extinction, unlike initial learning and extinction,…
Descriptors: Fear, Anxiety, Experimental Psychology, Learning
Post-Acquisition Release of Glutamate and Norepinephrine in the Amygdala Is Involved in Taste-Aversion Memory Consolidation
Peer reviewed Peer reviewed
Direct linkDirect link
Guzman-Ramos, Kioko; Osorio-Gomez, Daniel; Moreno-Castilla, Perla; Bermudez-Rattoni, Federico – Learning & Memory, 2012
Amygdala activity mediates the acquisition and consolidation of emotional experiences; we have recently shown that post-acquisition reactivation of this structure is necessary for the long-term storage of conditioned taste aversion (CTA). However, the specific neurotransmitters involved in such reactivation are not known. The aim of the present…
Descriptors: Short Term Memory, Reading Skills, Biochemistry, Emotional Experience
Serotonin Transporter Knockout Rats Show Improved Strategy Set-Shifting and Reduced Latent Inhibition
Peer reviewed Peer reviewed
Direct linkDirect link
Nonkes, Lourens J. P.; van de Vondervoort, Ilse I. G. M.; de Leeuw, Mark J. C.; Wijlaars, Linda P.; Maes, Joseph H. R.; Homberg, Judith R. – Learning & Memory, 2012
Behavioral flexibility is a cognitive process depending on prefrontal areas allowing adaptive responses to environmental changes. Serotonin transporter knockout (5-HTT[superscript -/-]) rodents show improved reversal learning in addition to orbitofrontal cortex changes. Another form of behavioral flexibility, extradimensional strategy set-shifting…
Descriptors: Inhibition, Brain, Cognitive Processes, Animals
The Effect of Interference on Temporal Order Memory for Random and Fixed Sequences in Nondemented Older Adults
Peer reviewed Peer reviewed
Direct linkDirect link
Tolentino, Jerlyn C.; Pirogovsky, Eva; Luu, Trinh; Toner, Chelsea K.; Gilbert, Paul E. – Learning & Memory, 2012
Two experiments tested the effect of temporal interference on order memory for fixed and random sequences in young adults and nondemented older adults. The results demonstrate that temporal order memory for fixed and random sequences is impaired in nondemented older adults, particularly when temporal interference is high. However, temporal order…
Descriptors: Young Adults, Older Adults, Memory, Learning Processes
Switching from Contextual to Tone Fear Conditioning and Vice Versa: The Key Role of the Glutamatergic Hippocampal-Lateral Septal Neurotransmission
Peer reviewed Peer reviewed
Direct linkDirect link
Calandreau, Ludovic; Desgranges, Bertrand; Jaffard, Robert; Desmedt, Aline – Learning & Memory, 2010
The aim of the present experiment was to directly assess the role of the glutamatergic hippocampal-lateral septal (HPC-LS) neurotransmission in tone and contextual fear conditioning. We found that pretraining infusion of glutamatergic acid into the lateral septum promotes tone conditioning and concomitantly disrupts contextual conditioning.…
Descriptors: Context Effect, Conditioning, Fear, Experiments