Given the underrepresentation of ethnic minorities in health research (Heiat et al. in "Arch Int Med" 162(15):1-17, 2002; Kelly et al. in "J Nat Med Assoc" 97:777-783, 2005; United States Department of Health and Human Services. "Monitoring adherence to the NIH policy on the inclusion of women and minorities as subjects in clinical research." http://orwh.od.nih.gov/research/inclusion/reports.asp, 2013), this study evaluated promising strategies to effectively recruit Latinos into genetic research on autism spectrum disorders (ASD). The study included 97 children, aged 5-17 years, with ASD; 82.5% of the participants were identified as Latino/Hispanic. Traditional and culture-specific recruitment and retention strategies were compared between the Latino and non-Latino groups. Culture-specific, parent-centered approaches were found to be successful in engaging and retaining Latino participants for research involving genetic testing.