The autistic syndrome is considered in the context of a disorder of brain development. The authors conclude that disruption of developmental loci most probably occurs in the end stages of neuronal development, after migrating neurons have reached their final place in the brain and are elaborating communicative processes. (Author)

There is a robust association between prenatal smoking and disruptive behavior disorders, but little is known about the emergence of such behaviors in early development. The association of prenatal smoking and hypothesized behavioral precursors to disruptive behavior in toddlers (N=93) was tested. Exposed toddlers demonstrated atypical behavioral…

The article presents a case history of a pair of male monozygotic twins who both had autism. During pregnancy the mother suffered from severe toxemia, and delivery occurred 2 months before term. (Author/DLS)

Children (N=434) with nonsyndromic mental retardation were analysed for frequency of prenatal, perinatal and infantile biological disturbances. Mildly retarded individuals of unrelated parentage, both idiopathic and familial, had a strikingly higher prevalence of disturbances than a control group of retarded individuals with consanguineous parents…

The article explores recent findings on Fatal Alcohol Syndrome (FAS), patterns of malformation, alcohol and other drugs, the toxicity of ethanol, the incidence of FAS, and implications of the syndrome. (Author)

The effects of alcohol on the developing fetus are examined. Noted is the existence of both structural problems (such as microcephaly and cardiac anomalies) and behavioral problems (such as mental retardation and speech and language deficits). The potential damage of alcohol at a very early stage of fetal development is discussed. It is thought…

The article reviews the literature on the relationship of certain viral diseases to hearing loss with emphasis on its implications for professionals who work with hearing impaired children and adults. The data describe both the serious pathology recently discovered to be present in some rubella deafened youth and the potential dangers of several…

Reported are causes of hearing loss for 41,109 hearing impaired students enrolled in 555 special educational programs as part of a national annual survey during the 1970-71 school year. Data is provided on the relationship between hearing loss etiology and the following variables: age and sex of students, additional handicapping conditions, family…

From 1973 to 1983 the number and proportion of mentally retarded persons in the total population of Sweden has not changed, but there are fewer children and young persons and more adults. The changes are hypothetically attributed to prenatal diagnosis, improved obstetrical techniques, and the introduction of antibiotics in 1948. (Author/VW)

Examination of 1,000 Finnish patients with mental retardation indicated that infectious diseases were the only cause of mental retardation in 11.1 percent and a contributory cause in a further 1.5 percent. Among the former group of 111 patients, the causative infectious disease operated prenatally in 18 percent and perinatally/postnatally in 82…

Pregnancy and delivery complications in the birth of 23 high-functioning autistic females and 23 high-functioning autistic males of similar intelligence quotient and age were compared with those of 54 normally developing siblings. Findings suggest that these factors may be less significant in high-functioning individuals than in severely retarded…

The booklet, written in Spanish, is intended to help parents of babies with cleft lip and/or cleft palate. Topics covered include the sequence of prenatal development and the effects of birth defects, common misconceptions about what causes the conditions, possible hereditary and environmental causes, and what it means to have a cleft palate or a…

Paper presented at the Annual Meeting of the American Association on Mental Deficiency (92nd, Boston, 1968).