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Au, Kit Sing; Ashley-Koch, Allison; Northrup, Hope – Developmental Disabilities Research Reviews, 2010
The worldwide incidence of neural tube defects (NTDs) ranges from 1.0 to 10.0 per 1,000 births with almost equal frequencies between two major categories: anencephaly and spina bifida (SB). Epidemiological studies have provided valuable insight for (a) researchers to identify nongenetic and genetic factors contributing to etiology, (b) public…
Descriptors: Prenatal Influences, Drug Use, Nutrition, Metabolism