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Kim, Bora; Ha, Mina; Kim, Young Shin; Koh, Yun-Joo; Dong, Shan; Kwon, Ho-Jang; Kim, Young-Suk; Lim, Myung-Ho; Paik, Ki-Chung; Yoo, Seung-Jin; Kim, Hosanna; Hong, Patricia S.; Sanders, Stephan J.; Leventhal, Bennett L. – Autism: The International Journal of Research and Practice, 2021
Genetics, environment, and their interactions impact autism spectrum disorder etiology. Smoking is a suspected autism spectrum disorder risk factor due to biological plausibility and high prevalence. Using two large epidemiological samples, we examined whether autism spectrum disorder was associated with prenatal paternal smoking in a Discovery…
Descriptors: Prenatal Influences, Pregnancy, Genetics, Environmental Influences
Pham, Cindy; Symeonides, Christos; O'Hely, Martin; Sly, Peter D.; Knibbs, Luke D.; Thomson, Sarah; Vuillermin, Peter; Saffery, Richard; Ponsonby, Anne-Louise – Autism: The International Journal of Research and Practice, 2022
Mounting evidence finds that early life environmental factors increased the probability of autism spectrum disorder. We estimated prospective associations between early life environmental factors and autism spectrum disorder symptoms in children at the age of 2 years in a population-derived birth cohort, the Barwon Infant Study. Autism spectrum…
Descriptors: Autism Spectrum Disorders, Symptoms (Individual Disorders), Preschool Children, Toddlers
Marceau, Kristine; Rolan, Emily; Leve, Leslie D.; Ganiban, Jody M.; Reiss, David; Shaw, Daniel S.; Natsuaki, Misaki N.; Egger, Helen L.; Neiderhiser, Jenae M. – Developmental Psychology, 2019
This study examines interactions of heritable influences, prenatal substance use, and postnatal parental warmth and hostility on the development of conduct problems in middle childhood for boys and girls. Participants are 561 linked families, collected in 2 cohorts, including birth parents, adoptive parents, and adopted children. Heritable…
Descriptors: Genetics, Substance Abuse, Prenatal Influences, Perinatal Influences
Kieling, Christian; Hutz, Mara H.; Genro, Julia P.; Polanczyk, Guilherme V.; Anselmi, Luciana; Camey, Suzi; Hallal, Pedro C.; Barros, Fernando C.; Victora, Cesar G.; Menezes, Ana M. B.; Rohde, Luis Augusto – Journal of Child Psychology and Psychiatry, 2013
Background: The study of gene-environment interactions (G by E) is one of the most promising strategies to uncover the origins of mental disorders. Replication of initial findings, however, is essential because there is a strong possibility of publication bias in the literature. In addition, there is a scarcity of research on the topic originated…
Descriptors: Genetics, Biochemistry, Prenatal Influences, Smoking
Wiebe, Sandra A.; Espy, Kimberly Andrews; Stopp, Christian; Respass, Jennifer; Stewart, Peter; Jameson, Travis R.; Gilbert, David G.; Huggenvik, Jodi I. – Developmental Psychology, 2009
Genetic factors dynamically interact with both pre- and postnatal environmental influences to shape development. Considerable attention has been devoted to gene-environment interactions (G x E) on important outcomes (A. Caspi & T. E. Moffitt, 2006). It is also important to consider the possibility that these G x E effects may vary across…
Descriptors: Smoking, Preschool Children, Neonates, Genetics
Altink, Marieke E.; Arias-Vasquez, Alejandro; Franke, Barbara; Slaats-Willemse, Dorine I. E.; Buschgens, Cathelijne J. M.; Rommelse, Nanda N. J.; Fliers, Ellen A.; Anney, Richard; Brookes, Keeley-Joanne; Chen, Wai; Gill, Michael; Mulligan, Aisling; Sonuga-Barke, Edmund; Thompson, Margaret; Sergeant, Joseph A.; Faraone, Stephen V.; Asherson, Philip; Buitelaar, Jan K. – Journal of Child Psychology and Psychiatry, 2008
Background: The dopamine receptor D4 ("DRD4") 7-repeat allele and maternal smoking during pregnancy are both considered as risk factors in the aetiology of attention deficit hyperactivity disorder (ADHD), but few studies have been conducted on their interactive effects in causing ADHD. The purpose of this study is to examine the gene by…
Descriptors: Siblings, Smoking, Attention Deficit Hyperactivity Disorder, Pregnancy
Howes, Carollee; Krakow, Joanne – 1977
This paper examines the effects of unavoidable pollutants on fetal development in humans. Inevitable pollutants such as radiation, pesticides, gases and lead found in the air, water, and food of our industrialized society are discussed as well as psychological correlates of industrialization and urbanization such as stress, increased noise levels…
Descriptors: Cognitive Development, Environmental Influences, Lead Poisoning, Perceptual Development
Goldman, Lynn R. – Zero to Three, 2005
Substances in the environment that are potentially harmful to children's health and development, from conception onward, include metals such as lead and mercury, pesticides, indoor air pollution, residues of synthetic chemicals, radiation from the sun, nuclear sources, and air pollution. Children's exposures to these substances, as well as…
Descriptors: Obesity, Family Violence, Child Health, Access to Health Care
Cheney, Carl D.; Phelps, Brady J. – 1990
The exact nature of the events which may predispose a person to substance abuse is not known. This paper provides a theoretical discussion and review which emphasizes three contexts which have been shown to predispose on individual to drug abuse: (1) prenatal exposure to a given substance; (2) environmental conditions present upon first exposure…
Descriptors: Alcohol Abuse, Behavior Patterns, Biological Influences, Drug Abuse
National Scientific Council on the Developing Child, 2006
New science shows that exposure to toxins prenatally or early in life can have a devastating and lifelong effect on the developing architecture of the brain. Exposures to many chemicals have much more severe consequences for embryos, fetuses, and young children, whose brains are still developing, than for adults. Substances that can have a truly…
Descriptors: Drug Abuse, Brain, Misconceptions, Poisoning