When evaluating the performance of Research and Development (R&D) and Scientific and Technological (S&T) transformation activities in universities, the existing studies do not contain prior strategy analysis and inequality analysis. In this regard, prior strategy reflects the relative attention paid by universities to R&D and S&T transformation activities, while inequality analysis assists us in better understanding technological inequality in efficiency across universities. Additionally, this study contributes to the existing literatures by proposing new concepts of window-based cross-efficiency, window-based relative weights and a network Data Envelopment Analysis model. Our framework is able to evaluate the efficiency, perform priority analysis and identify the sources of technological inequality. Empirically, this study focuses on universities in Chinese provinces from 2007 to 2019. This study is of high policy practice, since it provides policy makers with how each university has performed during the examined period and what are the underling factors driving efficiency changes.