In response to the COVID-19 pandemic, the Houston Independent School District (HISD) moved to remote learning, which included distance learning, independent study, live online meetings, and completing assignments online or paper-based packets mailed to the home beginning on March 30, 2020. The last nine weeks of the 2019-2020 school year were completed remotely. HISD extended remote learning through the 2020 summer school session and through the first six-week grading cycle of the 2020-2021 school year for all students. The 2020-2021 school year began remotely on September 8, 2020. The option for face-to-face instruction began on October 19, 2020, and parents had the option to choose remote or face-to-face instruction for the fall semester or the entire school year. It is important to understand how students enrolled in HISD performed academically for the second half of the 2019-2020 school year and the 2020-2021 school year, both as compared to the 2018-2019 school year (the most recent pre-pandemic school year) and as compared across different student groups within the district. This report analyzes the grades earned by students in the second semesters of the 2018-2019, 2019-2020, and 2020-2021 school years by grade level category, instructional mode (remote and face-to-face), race/ethnicity, student gender, and special populations including economically disadvantaged students, English learners, gifted/talented, special education, and homeless students. The report further disaggregates second semester grades by high school grade level (9th, 10th, 11th, and 12th) to ensure students are on track to fulfill high school graduation requirements.