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Rudnitskaya, Aleksandra; Torok, Bela; Torok, Marianna – Biochemistry and Molecular Biology Education, 2010
Molecular docking is a frequently used method in structure-based rational drug design. It is used for evaluating the complex formation of small ligands with large biomolecules, predicting the strength of the bonding forces and finding the best geometrical arrangements. The major goal of this advanced undergraduate biochemistry laboratory exercise…
Descriptors: Biochemistry, Science Instruction, Drug Therapy, Pharmacology
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Longtin, Sarah; Guilfoile, Patrick; Asper, Andrea – Journal of Biological Education, 2004
Bacterial antibiotic resistance remains a problem of clinical importance. Current microbiological methods for determining antibiotic resistance are based on culturing bacteria, and may require up to 48 hours to complete. Molecular methods are increasingly being developed to speed the identification of antibiotic resistance and to determine its…
Descriptors: Microbiology, Science Instruction, Molecular Biology, Drug Therapy