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Direct linkBattaglia, Agatino; Filippi, Tiziana; South, Sarah T.; Carey, John C. – Developmental Medicine & Child Neurology, 2009
To define the spectrum of epilepsy in Wolf-Hirschhorn syndrome (WHS) better, we studied 87 patients (54 females, 33 males; median age 5.6 years; age range 1-25.6 years) with confirmed 4p16.3 deletion. On the basis of clinical charts, we retrospectively analyzed the evolution of the electroencephalogram (EEG) findings and seizures. Epilepsy…
Descriptors: Age Differences, Epilepsy, Seizures, Identification
Blume, Warren T. – Mental Retardation and Developmental Disabilities Research Reviews, 2004
Lennox-Gastaut (L-G) syndrome is an intractable generalized epilepsy of childhood onset, associated with spike waves at a slow rate and paroxysmal fast activity. These epileptiform discharge patterns are thought to reflect excessive neocortical excitability and arise from neuronal and synaptic features peculiar to the immature central nervous…
Descriptors: Seizures, Brain, Social Isolation, Cognitive Development
